Duck Pulmonary Surfactant Associated Protein C ELISA Kit | SPC elisa kit

Duck Pulmonary Surfactant Associated Protein C ELISA Kit

• Gene Names: Sftpc; SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC
• Reactivity: Duck
• Synonyms: Pulmonary Surfactant Associated Protein C; Duck Pulmonary Surfactant Associated Protein C ELISA Kit; SPC elisa kit

• Reactivity: Duck

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 256355065
• NCBI GeneID: 20389
• NCBI Accession #: NP_035489.2
• NCBI GenBank Nucleotide #: NM_011359.2
• UniProt Accession #: P21841
• Molecular Weight: 21,055 Da
• NCBI Official Full Name: pulmonary surfactant-associated protein C
• NCBI Official Synonym Full Names: surfactant associated protein C
• NCBI Official Symbol: Sftpc
• NCBI Official Synonym Symbols: SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC
• NCBI Protein Information: pulmonary surfactant-associated protein C; pulmonary surfactant-associated proteolipid SPL(Val)
• UniProt Protein Name: Pulmonary surfactant-associated protein C
• UniProt Gene Name: Sftpc
• UniProt Synonym Gene Names: Sftp2; SP-C
• UniProt Entry Name: PSPC_MOUSE

Uniprot Description

SFTPC: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2); also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS); also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Cellular Component: multivesicular body; extracellular space; cytoplasm; extracellular region

Molecular Function: protein homodimerization activity

Biological Process: protein homooligomerization