Human Sperm Protein 17 Antibodies ELISA Kit | SP17A elisa kit

Human Sperm Protein 17 Antibodies ELISA Kit

Cat. Num. AAA16854

• Gene Names: SPACA3; CT54; LYC3; LYZL3; SLLP1; ALLP17; 1700025M08Rik
• Reactivity: Human
• Synonyms: Sperm Protein 17 Antibodies; Human Sperm Protein 17 Antibodies ELISA Kit; SP17A elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.
• Sequence Length: 215

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SP17A elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of Anti-SP17 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 27777653
• NCBI GeneID: 124912
• NCBI Accession #: NP_776246.1
• NCBI GenBank Nucleotide #: NM_173847.3
• UniProt Accession #: Q8IXA5; Q7Z4Y5
• Molecular Weight: 23,431 Da
• NCBI Official Full Name: sperm acrosome membrane-associated protein 3
• NCBI Official Synonym Full Names: sperm acrosome associated 3
• NCBI Official Symbol: SPACA3
• NCBI Official Synonym Symbols: CT54; LYC3; LYZL3; SLLP1; ALLP17; 1700025M08Rik
• NCBI Protein Information: sperm acrosome membrane-associated protein 3; lysozyme-like protein 3; cancer/testis antigen 54; sperm lysozyme like protein 1; sperm lysozyme-like protein 1; sperm protein reactive with ASA; sperm lyzozyme-like acrosomal protein 1; sperm protein reactive with antisperm antibodies; lysozyme-like sperm-specific secretory protein ALLP17; lysozyme-like acrosomal sperm-specific secretory protein ALLP-17
• UniProt Protein Name: Sperm acrosome membrane-associated protein 3
• UniProt Gene Name: SPACA3
• UniProt Synonym Gene Names: LYC3; LYZL3; SLLP1; SPRASA; CT54
• UniProt Entry Name: SACA3_HUMAN

Uniprot Description

SPACA3: a single-pass type II sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. A member of the Cancer-Testis Antigen (CTA) superfamily. CTAs may play roles in embryonal development and tumor transformation or aspects of tumor progression. CTAs were once thought to be silenced in most normal adult tissues, with limited expression in fetal, placental, testis, and ovarian cells. These proteins are now known to be aberrantly expressed in various cancers and many are capable of eliciting humoral and cellular immune responses. Expressed in testis, epididymis and placenta. Although it belongs to the glycosyl hydrolase 22 family, T122 and N139 are present instead of the conserved Glu and Asp which are active site residues. It is therefore expected that this protein lacks hydrolase activity. Two isoforms of the human protein are produced by alternative splicing. Note: This description may include information from RefSeq and UniProtKB

Protein type: Cancer Testis Antigen (CTA); Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: lysosome; integral to membrane; extracellular region; acrosomal membrane; secretory granule

Molecular Function: protein binding; lysozyme activity

Biological Process: sperm-egg recognition; defense response to Gram-positive bacterium; monocyte activation; response to virus; positive regulation of phagocytosis; cell wall catabolic process; peptidoglycan catabolic process; positive regulation of macrophage activation