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Typical Testing Data/Standard Curve (for reference only)

Chicken Suppressor of cytokine signaling 3 ELISA Kit | SOCS3 elisa kit

Chicken Suppressor of cytokine signaling 3 ELISA Kit

Gene Names
SOCS3; null
Reactivity
Chicken
Synonyms
Suppressor of cytokine signaling 3; Chicken Suppressor of cytokine signaling 3 ELISA Kit; SOCS-3; SOCS3; SOCS3 elisa kit
Ordering
For Research Use Only!
Reactivity
Chicken
Sequence Length
209
Detection Range
78-5000 pg/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,176 Da
NCBI Official Full Name
suppressor of cytokine signaling 3
NCBI Official Synonym Full Names
suppressor of cytokine signaling 3
NCBI Official Symbol
SOCS3
NCBI Official Synonym Symbols
null
NCBI Protein Information
suppressor of cytokine signaling 3
UniProt Protein Name
Suppressor of cytokine signaling 3
UniProt Gene Name
SOCS3
UniProt Synonym Gene Names
SOCS-3
UniProt Entry Name
SOCS3_CHICK

Uniprot Description

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin and leptin receptors (). Binding to JAK2 inhibits its kinase activity (). Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells (). Regulates IL-6 signaling in vivo. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST ().

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Product Notes

The Chicken SOCS3 socs3 (Catalog #AAA289774) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289774 ELISA Kit recognizes Chicken SOCS3. It is sometimes possible for the material contained within the vial of "Suppressor of cytokine signaling 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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