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Sperm motility kinase Tcr mutant form (Smoktcr) Recombinant Protein | Smoktcr recombinant protein

Recombinant Mouse Sperm motility kinase Tcr mutant form (Smoktcr)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Sperm motility kinase Tcr mutant form (Smoktcr); Recombinant Mouse Sperm motility kinase Tcr mutant form (Smoktcr); Smoktcr recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-484, full length protein
Sequence
MEKFHAQYEMLETIGQGGCAQVKLARHRLTGTHVAVKVIVKRECWFNPVMSEAELLMMTDHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIQNAGYLQEDEARPLFKQLLSAMNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPGQNHNLFCEIYPFSTPEVLFNRPYDMRKIDVWGLGVVLYFMVTGKILFDTASVEKLRKQIVAEKCSVPCRLSVELQDLIRLLMTDIPELRPTVAEVMVHPWVTEGSGVLPDPCEEHIPLKPDPAIAKAMGFIGFQAQDIEDSLCQRKFNETMASYCLLKKQILKECDRPIRAQPMNPSVTPLSSLVDAPTFHLGLRRTETEPTGLRLSDNKEVPVCGNSTSKKRERSFSGPGVLSRPINTTPTMDQTHTRTWSGPCIYSNVCTIHPNSINESTEGHISTSAEDKPVHSRGWPRGIKGWTRKIGNAMRKLCCCIPSKETSHLGQRRVCPKI
Sequence Length
484
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
54,619 Da
NCBI Official Full Name
Sperm motility kinase Tcr mutant form
UniProt Protein Name
Sperm motility kinase Tcr mutant form
Protein Family
UniProt Gene Name
Smoktcr
UniProt Synonym Gene Names
SmokTcr; Tcr

Uniprot Description

While the main function of Smoks is to control sperm motility, the role of Smok-Tcr, with reduced kinase activity, is to counterbalance a signaling impairment caused by the distorter/sterility loci, giving t-sperm an advantage in reaching the oocytes. Transmission ratio distortion also called segregation distortion is the name given to the phenomenon above-mentioned. Being associated with the T-complex, it allows males heterozygous for a complete t-haplotype to preferentially transmit the t-haplotype chromosome.

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Product Notes

The Smoktcr smoktcr (Catalog #AAA1013737) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-484, full length protein. The amino acid sequence is listed below: MEKFHAQYEM LETIGQGGCA QVKLARHRLT GTHVAVKVIV KRECWFNPVM SEAELLMMTD HPNIISLLQV IETKKKVYLI MELCEGKSLY QHIQNAGYLQ EDEARPLFKQ LLSAMNYCHN QGIVHRDLTP DNIMVEKDGK VKIIDFGLGT QEKPGQNHNL FCEIYPFSTP EVLFNRPYDM RKIDVWGLGV VLYFMVTGKI LFDTASVEKL RKQIVAEKCS VPCRLSVELQ DLIRLLMTDI PELRPTVAEV MVHPWVTEGS GVLPDPCEEH IPLKPDPAIA KAMGFIGFQA QDIEDSLCQR KFNETMASYC LLKKQILKEC DRPIRAQPMN PSVTPLSSLV DAPTFHLGLR RTETEPTGLR LSDNKEVPVC GNSTSKKRER SFSGPGVLSR PINTTPTMDQ THTRTWSGPC IYSNVCTIHP NSINESTEGH ISTSAEDKPV HSRGWPRGIK GWTRKIGNAM RKLCCCIPSK ETSHLGQRRV CPKI. It is sometimes possible for the material contained within the vial of "Sperm motility kinase Tcr mutant form (Smoktcr), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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