Mouse structural maintenance of chromosomes 4 ELISA Kit | SMC4 elisa kit
Mouse Structural maintenance of chromosomes protein 4, SMC4 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SMC4: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Forms an heterodimer with SMC2. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG. Widely expressed. Higher expression in testis, colon, thymus. Belongs to the SMC family. SMC4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Cellular Component: nucleoplasm; cytoplasm; condensin complex; chromosome; nucleus
Molecular Function: protein binding; protein heterodimerization activity; nucleotide binding; ATP binding
Biological Process: chromosome condensation; mitosis; meiotic chromosome condensation; cell division; mitotic chromosome condensation; cell cycle; chromosome organization and biogenesis; kinetochore organization and biogenesis; meiotic chromosome segregation
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Product Notes
The Mouse SMC4 smc4 (Catalog #AAA9340624) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340624 ELISA Kit recognizes Mouse SMC4. It is sometimes possible for the material contained within the vial of "structural maintenance of chromosomes 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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