Rat structural maintenance of chromosomes 1A ELISA Kit | SMC1A elisa kit
Rat Structural maintenance of chromosomes protein 1A, SMC1A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
structural maintenance of chromosomes (SMC) protein, one of 2 component proteins forming the cohesin multiprotein complex required for sister chromatid cohesion; thought to be a component of functional kinetochores [RGD, Feb 2006]
Uniprot Description
Smc1: a component of the cohesin multiprotein complex that is required for sister chromatid cohesion. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Thought to be an important part of functional kinetochores. Interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair.
Protein type: DNA replication; RNA splicing
Cellular Component: kinetochore; nucleoplasm; cohesin core heterodimer; cytoplasm; nucleolus; nucleus
Molecular Function: protein heterodimerization activity; chromatin binding; ATP binding
Biological Process: meiosis; response to radiation; cell division; mitotic cell cycle checkpoint; mitotic sister chromatid cohesion; stem cell maintenance; sister chromatid cohesion; DNA damage response, signal transduction; negative regulation of DNA endoreduplication; DNA repair
Research Articles on SMC1A
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Product Notes
The Rat SMC1A smc1a (Catalog #AAA9320481) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320481 ELISA Kit recognizes Rat SMC1A. It is sometimes possible for the material contained within the vial of "structural maintenance of chromosomes 1A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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