Human secreted LY6/PLAUR domain containing 1 ELISA Kit | SLURP1 elisa kit
Human Secreted Ly-6/uPAR-related protein 1, SLURP1 ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors. [provided by RefSeq, Jul 2008]
Uniprot Description
SLURP1: Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. Defects in SLURP1 are a cause of Mal de Meleda (MDM); also known as keratosis palmoplantaris transgradiens of Siemens. MDM is a rare autosomal recessive skin disorder, characterized by diffuse transgressive palmoplantar keratoderma with keratotic lesions extending onto the dorsa of the hands and the feet (transgrediens). Patients may have hyperhidrosis. Other features include perioral erythema, lichenoid plaques on the knees and the elbows, and nail abnormalities.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: extracellular space; extracellular region
Molecular Function: cytokine activity
Biological Process: neuromuscular process controlling posture; cell activation; locomotory behavior; cell adhesion
Disease: Mal De Meleda
Research Articles on SLURP1
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Product Notes
The Human SLURP1 slurp1 (Catalog #AAA942137) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA942137 ELISA Kit recognizes Human SLURP1. It is sometimes possible for the material contained within the vial of "secreted LY6/PLAUR domain containing 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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