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Typical Testing Data/Standard Curve (for reference only)

Human secreted LY6/PLAUR domain containing 1 ELISA Kit | SLURP1 elisa kit

Human Secreted Ly-6/uPAR-related protein 1, SLURP1 ELISA Kit

Gene Names
SLURP1; ARS; MDM; ANUP; ArsB; LY6LS
Reactivity
Human
Synonyms
secreted LY6/PLAUR domain containing 1; Human Secreted Ly-6/uPAR-related protein 1; SLURP1 ELISA Kit; Human Secreted Ly-6/uPAR-related protein 1 (SLURP1) ELISA kit; ANUP; ARS; ArsB; LY6LS; MDM; ARS component B; ARS (component B) -81/S; anti-neoplastic urinary protein; lymphocyte antigen 6-like secreted; secreted Ly6/uPAR related protein 1; SLURP1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human SLURP1. No significant cross-reactivity or interference between Human SLURP1 and analogues was observed.
Sequence Length
103
Samples
Serum, plasma, tissue homogenates
Assay Type
Sandwich
Detection Range
4.69 ng/ml-300 ng/ml
Sensitivity
1.17 ng/ml
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Detection Wavelength
450 nm
Sample Volume
50-100ul
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for SLURP1 elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SLURP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SLURP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SLURP1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SLURP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,186 Da
NCBI Official Full Name
secreted Ly-6/uPAR-related protein 1
NCBI Official Synonym Full Names
secreted LY6/PLAUR domain containing 1
NCBI Official Symbol
SLURP1
NCBI Official Synonym Symbols
ARS; MDM; ANUP; ArsB; LY6LS
NCBI Protein Information
secreted Ly-6/uPAR-related protein 1; SLURP-1; ARS(component B)-81/S; anti-neoplastic urinary protein; lymphocyte antigen 6-like secreted; secreted Ly6/uPAR related protein 1
UniProt Protein Name
Secreted Ly-6/uPAR-related protein 1
UniProt Gene Name
SLURP1
UniProt Synonym Gene Names
ARS; SLURP-1; ANUP
UniProt Entry Name
SLUR1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors. [provided by RefSeq, Jul 2008]

Uniprot Description

SLURP1: Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. Defects in SLURP1 are a cause of Mal de Meleda (MDM); also known as keratosis palmoplantaris transgradiens of Siemens. MDM is a rare autosomal recessive skin disorder, characterized by diffuse transgressive palmoplantar keratoderma with keratotic lesions extending onto the dorsa of the hands and the feet (transgrediens). Patients may have hyperhidrosis. Other features include perioral erythema, lichenoid plaques on the knees and the elbows, and nail abnormalities.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: extracellular space; extracellular region

Molecular Function: cytokine activity

Biological Process: neuromuscular process controlling posture; cell activation; locomotory behavior; cell adhesion

Disease: Mal De Meleda

Research Articles on SLURP1

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Product Notes

The Human SLURP1 slurp1 (Catalog #AAA942137) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA942137 ELISA Kit recognizes Human SLURP1. It is sometimes possible for the material contained within the vial of "secreted LY6/PLAUR domain containing 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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