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Pre-mRNA-splicing factor SLU7 (Slu7) Recombinant Protein | Slu7 recombinant protein

Recombinant Rat Pre-mRNA-splicing factor SLU7 (Slu7)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Pre-mRNA-splicing factor SLU7 (Slu7); Recombinant Rat Pre-mRNA-splicing factor SLU7 (Slu7); Slu7 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-586, full length protein
Sequence
SAAAVDPVSATPMTGSKEMNLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSITTKYRKGACENCGAMTHKRKDCFERPRRVGAKFTGTNIAPDEHIQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKINNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKESVNSEECIINDATGEEPVKKPQTLMELHQEKLKEEKKKKKKKKKHRKSSSDSDDDEERKQEKLKKALNAEEARLLHVKEIMQVDERKRPYNSIYETREPTEEEMEAYRMKRQRPDDPMASFLGQ
Sequence Length
585
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Slu7 recombinant protein
Pre-mRNA splicing occurs in two sequential transesterification steps. This protein is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68,337 Da
NCBI Official Full Name
pre-mRNA-splicing factor SLU7
NCBI Official Synonym Full Names
SLU7 homolog, splicing factor
NCBI Official Symbol
Slu7
NCBI Protein Information
pre-mRNA-splicing factor SLU7
UniProt Protein Name
Pre-mRNA-splicing factor SLU7
Protein Family
UniProt Gene Name
Slu7

NCBI Description

human homolog is a splicing factor required for selection of the correct AG dinucleotide at the 3 splice site in the second catalytic step of mRNA splicing [RGD, Feb 2006]

Uniprot Description

Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation ().

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Product Notes

The Slu7 slu7 (Catalog #AAA1449671) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-586, full length protein. The amino acid sequence is listed below: SAAAVDPVSA TPMTGSKEMN LEEPKKMTRE DWRKKKELEE QRKLGNAPAE VDEEGKDINP HIPQYISSVP WYIDPSKRPT LKHQRPQPEK QKQFSSSGEW YKRGVKENSI TTKYRKGACE NCGAMTHKRK DCFERPRRVG AKFTGTNIAP DEHIQPQLMF DYDGKRDRWN GYNPEEHMKI VEEYAKVDLA KRTLKAQKLQ EELASGKLVE QANSPKHQWG EEEPNSQMEK DHNSEDEDED KYADDIDMPG QNFDSKRRIT VRNLRIREDI AKYLRNLDPN SAYYDPKTRA MRENPYANAG KNPDEVSYAG DNFVRYTGDT ISMAQTQLFA WEAYDKGSEV HLQADPTKLE LLYKSFKVKK EDFKEQQKES ILEKYGGQEH LDAPPAELLL AQTEDYVEYS RHGTVIKGQE RAVACSKYEE DVKINNHTHI WGSYWKEGRW GYKCCHSFFK YSYCTGEAGK ESVNSEECII NDATGEEPVK KPQTLMELHQ EKLKEEKKKK KKKKKHRKSS SDSDDDEERK QEKLKKALNA EEARLLHVKE IMQVDERKRP YNSIYETREP TEEEMEAYRM KRQRPDDPMA SFLGQ. It is sometimes possible for the material contained within the vial of "Pre-mRNA-splicing factor SLU7 (Slu7), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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