Pre-mRNA-splicing factor SLU7 (Slu7) Recombinant Protein | Slu7 recombinant protein
Recombinant Rat Pre-mRNA-splicing factor SLU7 (Slu7)
NCBI and Uniprot Product Information
NCBI Description
human homolog is a splicing factor required for selection of the correct AG dinucleotide at the 3 splice site in the second catalytic step of mRNA splicing [RGD, Feb 2006]
Uniprot Description
Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation ().
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Product Notes
The Slu7 slu7 (Catalog #AAA1449671) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-586, full length protein. The amino acid sequence is listed below: SAAAVDPVSA TPMTGSKEMN LEEPKKMTRE DWRKKKELEE QRKLGNAPAE VDEEGKDINP HIPQYISSVP WYIDPSKRPT LKHQRPQPEK QKQFSSSGEW YKRGVKENSI TTKYRKGACE NCGAMTHKRK DCFERPRRVG AKFTGTNIAP DEHIQPQLMF DYDGKRDRWN GYNPEEHMKI VEEYAKVDLA KRTLKAQKLQ EELASGKLVE QANSPKHQWG EEEPNSQMEK DHNSEDEDED KYADDIDMPG QNFDSKRRIT VRNLRIREDI AKYLRNLDPN SAYYDPKTRA MRENPYANAG KNPDEVSYAG DNFVRYTGDT ISMAQTQLFA WEAYDKGSEV HLQADPTKLE LLYKSFKVKK EDFKEQQKES ILEKYGGQEH LDAPPAELLL AQTEDYVEYS RHGTVIKGQE RAVACSKYEE DVKINNHTHI WGSYWKEGRW GYKCCHSFFK YSYCTGEAGK ESVNSEECII NDATGEEPVK KPQTLMELHQ EKLKEEKKKK KKKKKHRKSS SDSDDDEERK QEKLKKALNA EEARLLHVKE IMQVDERKRP YNSIYETREP TEEEMEAYRM KRQRPDDPMA SFLGQ. It is sometimes possible for the material contained within the vial of "Pre-mRNA-splicing factor SLU7 (Slu7), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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