Mouse solute carrier family 9 (sodium/hydrogen exchanger) , member 3 regulator 2 ELISA Kit | SLC9A3R2 elisa kit
Mouse Na (+) /H (+) exchange regulatory cofactor NHE-RF2
NCBI and Uniprot Product Information
Uniprot Description
NHERF-2: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. Homodimer, and heterodimer with SLC9A3R1. Binds PDZK1. Found in a complex with EZR, PODXL and SLC9A3R2. Interacts (via the PDZ domains) with PODXL (via the C-terminal PDZ-binding motif DTHL); interaction is detected in glomerular epithelium cells. Binds ADRB2, SLC9A3, P2RY1, P2YR2, SRY, RDX and LPAR2. Interacts with MCC and PODXL. Interacts with SGK1 and KCNJ1/ROMK1. Widely expressed. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Cellular Component: stereocilium; stereocilium bundle; focal adhesion; protein complex; membrane; cytoplasm; apical plasma membrane; plasma membrane; nucleus
Molecular Function: protein C-terminus binding; protein binding; low-density lipoprotein receptor binding; channel regulator activity; beta-catenin binding; protein complex scaffold; PDZ domain binding; receptor binding; phosphatase binding
Biological Process: sensory perception of sound; positive regulation of membrane potential; negative regulation of phosphoinositide 3-kinase cascade
Research Articles on SLC9A3R2
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Product Notes
The Mouse SLC9A3R2 slc9a3r2 (Catalog #AAA9332105) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9332105 ELISA Kit recognizes Mouse SLC9A3R2. It is sometimes possible for the material contained within the vial of "solute carrier family 9 (sodium/hydrogen exchanger) , member 3 regulator 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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