Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (Slc9a3r1) Recombinant Protein | Slc9a3r1 recombinant protein

Recombinant Mouse Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (Slc9a3r1)

Cat. Num. AAA950625

• Gene Names: Slc9a3r1; EBP-50; NHE-RF; NHERF1; NHERF-1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (Slc9a3r1); Recombinant Mouse Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (Slc9a3r1); Slc9a3r1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-355, Full length protein
• Sequence: SADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREELLRPQEKSEQAEPPAAADTHEAGDQNEAEKSHLRELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEFFKKCKVIPSQEHLDGPLPEPFSNGEIQKESSREALVEPASESPRPALARSASSDTSEELNSQDSPKRQVSTEPSSTSSSSSDPILDLNISLAVAKERAHQKRSSKRAPQMDWSKKNELFSNL
• Sequence Length: 354

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 6755566
• NCBI GeneID: 26941
• NCBI Accession #: NP_036160.1
• NCBI GenBank Nucleotide #: NM_012030.2
• UniProt Accession #: P70441; Q8BYD8
• Molecular Weight: 4,429 Da
• NCBI Official Full Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
• NCBI Official Synonym Full Names: solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
• NCBI Official Symbol: Slc9a3r1
• NCBI Official Synonym Symbols: EBP-50; NHE-RF; NHERF1; NHERF-1
• NCBI Protein Information: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
• UniProt Protein Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
• Protein Family: Na(+)/H(+) exchange regulatory cofactor
• UniProt Gene Name: Slc9a3r1
• UniProt Synonym Gene Names: Nherf; Nherf1; NHERF-1; EBP50

Uniprot Description

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling (). May participate in HTR4 targeting to microvilli. Involved in the regulation of phosphate reabsorption in the renal proximal tubules (). Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.