Mouse solute carrier family 4, sodium bicarbonate cotransporter, member 8 ELISA Kit | SLC4A8 elisa kit
Mouse Electroneutral sodium bicarbonate exchanger 1, SLC4A8 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SLC4A8: Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity. Belongs to the anion exchanger (TC 2.A.31) family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Cellular Component: neuron projection; membrane; integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: inorganic anion exchanger activity; transporter activity; anion:anion antiporter activity; anion transmembrane transporter activity; sodium:bicarbonate symporter activity; antiporter activity
Biological Process: embryonic development; transport; bicarbonate transport; regulation of intracellular pH; sodium ion transport; ion transport; anion transport
Research Articles on SLC4A8
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Product Notes
The Mouse SLC4A8 slc4a8 (Catalog #AAA9322654) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322654 ELISA Kit recognizes Mouse SLC4A8. It is sometimes possible for the material contained within the vial of "solute carrier family 4, sodium bicarbonate cotransporter, member 8, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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