Mouse solute carrier family 20 (phosphate transporter) , member 2 ELISA Kit | SLC20A2 elisa kit
Mouse Sodium-dependent phosphate transporter 2, SLC20A2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SLC20A2: Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants. Defects in SLC20A2 are the cause of basal ganglia calcification, idiopathic, type 3 (IBGC3). An autosomal dominant condition characterized by symmetric calcification in the basal ganglia and other brain regions. Affected individuals can either be asymptomatic or show a wide spectrum of neuropsychiatric symptoms, including parkinsonism, dystonia, tremor, ataxia, dementia, psychosis, seizures, and chronic headache. Serum levels of calcium, phosphate, alkaline phosphatase and parathyroid hormone are normal. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
Protein type: Membrane protein, integral; Receptor, misc.; Transporter; Membrane protein, multi-pass; Transporter, SLC family
Cellular Component: membrane; plasma membrane; integral to membrane
Molecular Function: symporter activity; inorganic phosphate transmembrane transporter activity
Biological Process: phosphate transport; viral reproduction; transport; sodium ion transport; ion transport
Research Articles on SLC20A2
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Product Notes
The Mouse SLC20A2 slc20a2 (Catalog #AAA9321805) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321805 ELISA Kit recognizes Mouse SLC20A2. It is sometimes possible for the material contained within the vial of "solute carrier family 20 (phosphate transporter) , member 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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