CD353 recombinant protein

CD353 Recombinant Protein

Cat. Num. AAA3004301

• Gene Names: SLAMF8; BLAME; CD353; SBBI42
• Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is >85% (by SDS-PAGE).
• Synonyms: CD353; CD353 Recombinant Protein; CD353 recombinant protein

• Host: E Coli
• Purity/Purification: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is >85% (by SDS-PAGE).
• Form/Format: PBS, 4M Urea, PH7.4
• Concentration: >=0.5mg/ml (varies by lot)
• Sequence: AQVLSKVGGSVLLVAARPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRAQLHSNLSLELGPLESGDSGNFSVLMVDTRGQPWTQTLQLKVYDAVPRPVVQVFIAVERDAQPSKTCQVFLSCWAPNISEITYSWRRETTMDFGMEPHSLFTDGQVLSISLGPGDRDVAYSCIVSNPVSWDLATVTPWDSCHHEAAPGKASYKD

• Tag: His-tag in C-terminal
• Expression Vector: pet-22b(+)
• BP: 645
• Restriction Site: NdeI-XhoI
• Preparation and Storage: Store at 4 degee C for short term. Aliquot and store at -20 degee C long term. Avoid freeze-thaw cycles.

Testing Data

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Related Product Information for CD353 recombinant protein

Background: SLAMF8, may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.

NCBI and Uniprot Product Information

• NCBI GI #: 9910342
• NCBI GeneID: 56833
• NCBI Accession #: NP_064510.1
• NCBI GenBank Nucleotide #: NM_020125.2
• UniProt Accession #: Q9P0V8; Q32MC6; Q5VU15
• Molecular Weight: 19,707 Da
• NCBI Official Full Name: SLAM family member 8
• NCBI Official Synonym Full Names: SLAM family member 8
• NCBI Official Symbol: SLAMF8
• NCBI Official Synonym Symbols: BLAME; CD353; SBBI42
• NCBI Protein Information: SLAM family member 8; BCM-like membrane protein; B lymphocyte activator macrophage expressed; B-lymphocyte activator macrophage expressed
• UniProt Protein Name: SLAM family member 8
• UniProt Gene Name: SLAMF8
• UniProt Synonym Gene Names: BLAME
• UniProt Entry Name: SLAF8_HUMAN

NCBI Description

This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008]

Uniprot Description

SLAMF8: May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: integral to membrane

Molecular Function: receptor activity

Biological Process: regulation of kinase activity; regulation of NAD(P)H oxidase activity; defense response to bacterium