Mouse sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) ELISA Kit | SIRT5 elisa kit
Mouse NAD-dependent deacetylase sirtuin-5, SIRT5 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SIRT5: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Has weak NAD- dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro. Belongs to the sirtuin family. Class III subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; EC 3.5.1.-; Deacetylase
Cellular Component: mitochondrion; mitochondrial matrix; cytoplasm; mitochondrial intermembrane space; nucleus; cytosol
Molecular Function: (3,5-dichlorophenylurea)acetate amidohydrolase activity; zinc ion binding; hydrolase activity; metal ion binding; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity; N-acetylgalactosamine-6-phosphate deacetylase activity; N2-acetyl-L-lysine deacetylase activity; protein binding; iprodione amidohydrolase activity; indoleacetamide hydrolase activity; protein N-terminal asparagine amidohydrolase activity; histone deacetylase activity; O-succinylbenzoate synthase activity
Research Articles on SIRT5
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Product Notes
The Mouse SIRT5 sirt5 (Catalog #AAA9317577) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317577 ELISA Kit recognizes Mouse SIRT5. It is sometimes possible for the material contained within the vial of "sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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