Sheep CD177 antigen (CD177) ELISA Kit | CD177 elisa kit
Sheep CD177 antigen (CD177) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
Uniprot Description
CD177: Induced by CSF3 in resting granulocytes. Induced in patients with polycythemia vera (PV) and with essential thrombocythemia (ET). 3 isoforms of the human protein are produced by alternative splicing
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: plasma membrane
Biological Process: blood coagulation; leukocyte migration
Research Articles on CD177
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Product Notes
The Sheep CD177 cd177 (Catalog #AAA7228072) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7228072 ELISA Kit recognizes Sheep CD177. It is sometimes possible for the material contained within the vial of "CD177 antigen (CD177), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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