Mouse SH3 domain containing ring finger 1 ELISA Kit | SH3RF1 elisa kit
Mouse Putative E3 ubiquitin-protein ligase SH3RF1, SH3RF1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SH3RF1: Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. Belongs to the SH3RF family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system; Ligase; EC 6.3.2.19; EC 6.3.2.-; Adaptor/scaffold; Ubiquitin ligase
Cellular Component: Golgi apparatus; cell projection; cytoplasm; cytosol
Molecular Function: protein binding; zinc ion binding; coenzyme F420-2 alpha-glutamyl ligase activity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; metal ion binding; ribosomal S6-glutamic acid ligase activity; coenzyme F420-0 gamma-glutamyl ligase activity; ligase activity
Biological Process: apoptosis; negative regulation of caspase activity; regulation of JNK cascade; negative regulation of apoptosis
Research Articles on SH3RF1
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Product Notes
The Mouse SH3RF1 sh3rf1 (Catalog #AAA9341015) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9341015 ELISA Kit recognizes Mouse SH3RF1. It is sometimes possible for the material contained within the vial of "SH3 domain containing ring finger 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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