Rat serum/glucocorticoid regulated kinase 2 ELISA Kit | SGK2 elisa kit
Rat Serine/threonine-protein kinase Sgk2, SGK2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
human homolog induces activation of the epithelial sodium channel ENaC [RGD, Feb 2006]
Uniprot Description
SGK2: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Highly expressed in liver, kidney and pancreas, and at lower levels in brain. Two specific sites, one in the kinase domain (Thr-253) and the other in the C-terminal regulatory region (Ser- 416), need to be phsphorylated for its full activation. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.11.1; Protein kinase, AGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); AGC group; SGK family
Cellular Component: cytoplasm; nucleus
Molecular Function: protein serine/threonine kinase activity; potassium channel regulator activity; ATP binding
Biological Process: protein amino acid phosphorylation
Research Articles on SGK2
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Product Notes
The Rat SGK2 sgk2 (Catalog #AAA9318734) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318734 ELISA Kit recognizes Rat SGK2. It is sometimes possible for the material contained within the vial of "serum/glucocorticoid regulated kinase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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