Rat SET domain and mariner transposase fusion gene ELISA Kit | SETMAR elisa kit
Rat Histone-lysine N-methyltransferase SETMAR, SETMAR ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a histone-lysine N-methyltransferase that may be involved in the methylation of histone H3. In anthropoid primates this gene is a fusion gene of a SET histone-lysine N-methyltransferase and a mariner (MAR) family transposase. In all other species this gene contains only the SET domain. [provided by RefSeq, Feb 2013]
Uniprot Description
SETMAR: Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Methyltransferase, protein lysine; Amino Acid Metabolism - lysine degradation; EC 2.1.1.43; Methyltransferase
Cellular Component: condensed chromosome; chromosome; nucleus
Molecular Function: structure-specific DNA binding; protein homodimerization activity; zinc ion binding; single-stranded DNA specific endodeoxyribonuclease activity; histone lysine N-methyltransferase activity (H3-K4 specific); endonuclease activity; double-stranded DNA binding; histone-lysine N-methyltransferase activity; single-stranded DNA binding; histone lysine N-methyltransferase activity (H3-K36 specific)
Biological Process: cell proliferation; DNA integration; histone H3-K4 methylation; DNA double-strand break processing; histone H3-K36 methylation; DNA catabolic process, endonucleolytic; double-strand break repair via nonhomologous end joining; replication fork processing
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Product Notes
The Rat SETMAR setmar (Catalog #AAA9318423) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318423 ELISA Kit recognizes Rat SETMAR. It is sometimes possible for the material contained within the vial of "SET domain and mariner transposase fusion gene, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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