Sentrin-specific protease 1 (Senp1) Recombinant Protein | Senp1 recombinant protein
Recombinant Mouse Sentrin-specific protease 1 (Senp1)
Gene Names
Senp1; suPr-2; D15Ertd528e; 2310046A20Rik; E330036L07Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Sentrin-specific protease 1 (Senp1); Recombinant Mouse Sentrin-specific protease 1 (Senp1); Senp1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-640, Full length protein
Sequence
MDDTADGVKMDAGEVTLVNHGSTFRTHRPPQSGFPEEQLLLSDQQSLPFRQGTLDGSFTCSTRSPAYRPDYHSDNPSSDSFLGSGDVRTFGQSANGQWRNSTPASGSAPQKPRNSRSLCLETRKTSSGLSNTFVGKSNHHCHMSAYEKSFPIKPAPSPSWSGSCRRSLLSPKKTQRRHFSTAEETVQEEEKEIYRQLLQMVTGKQFCVAKPTTHFPLRLSRCLSSNKNSLKDSLLRNGNSCASHVIGSDTSSSGSASILTAQEQLSHSAHSLSSGTPDVAFGSKDSDPHHHLAAPHQPNSLPASNTQSEGSDSVILLKVKESQTPASSPTFFQAELWIKELTSVYDSRARERLRRIEEQKALALQLQNQRLQEQEHAVLDSVELHLRVPLEKEIPVTAAQETRKKSHQLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGFPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRRKSITYYDSMGGINNEACRILLQYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
Sequence Length
640
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72,511 Da
NCBI Official Full Name
sentrin-specific protease 1
NCBI Official Synonym Full Names
SUMO1/sentrin specific peptidase 1
NCBI Official Symbol
Senp1
NCBI Official Synonym Symbols
suPr-2; D15Ertd528e; 2310046A20Rik; E330036L07Rik
NCBI Protein Information
sentrin-specific protease 1
UniProt Protein Name
Sentrin-specific protease 1
Protein Family
UniProt Gene Name
Senp1
UniProt Synonym Gene Names
Supr2; SuPr-2
Uniprot Description
Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 ().
Research Articles on Senp1
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Product Notes
The Senp1 senp1 (Catalog #AAA951554) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-640, Full length protein. The amino acid sequence is listed below: MDDTADGVKM DAGEVTLVNH GSTFRTHRPP QSGFPEEQLL LSDQQSLPFR QGTLDGSFTC STRSPAYRPD YHSDNPSSDS FLGSGDVRTF GQSANGQWRN STPASGSAPQ KPRNSRSLCL ETRKTSSGLS NTFVGKSNHH CHMSAYEKSF PIKPAPSPSW SGSCRRSLLS PKKTQRRHFS TAEETVQEEE KEIYRQLLQM VTGKQFCVAK PTTHFPLRLS RCLSSNKNSL KDSLLRNGNS CASHVIGSDT SSSGSASILT AQEQLSHSAH SLSSGTPDVA FGSKDSDPHH HLAAPHQPNS LPASNTQSEG SDSVILLKVK ESQTPASSPT FFQAELWIKE LTSVYDSRAR ERLRRIEEQK ALALQLQNQR LQEQEHAVLD SVELHLRVPL EKEIPVTAAQ ETRKKSHQLT DSEDEFPEIT EEMEKEIKNV FRNGNQDEVL SEAFRLTITR KDIQTLNHLN WLNDEIINFY MNMLMERSKE KGFPSVHAFN TFFFTKLKTA GYQAVKRWTK KVDVFSVDIL LVPIHLGVHW CLAVVDFRRK SITYYDSMGG INNEACRILL QYLKQESVDK KRKEFDTNGW QLFSKKSQEI PQQMNGSDCG MFACKYADCI TKDRPINFTQ QHMPYFRKRM VWEILHRKLL. It is sometimes possible for the material contained within the vial of "Sentrin-specific protease 1 (Senp1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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