P-selectin glycoprotein ligand 1 (Selplg) Recombinant Protein | Selplg recombinant protein

Recombinant Mouse P-selectin glycoprotein ligand 1 (Selplg), partial

Cat. Num. AAA1369145

• Gene Names: Selplg; CD162; Psgl1; Selp1; Selpl; Psgl-1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: P-selectin glycoprotein ligand 1 (Selplg); Recombinant Mouse P-selectin glycoprotein ligand 1 (Selplg); partial; Selplg recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 18-307
• Sequence: LQL QDPWGHETKE APGPVHLRER RQVVGDDDFE DPDYTYNTDP PELLKNVTNT VAAHPELPTT VVMLERDSTS AGTSERATEK IATTDPTAPG TGGTAVGMLS TDSATQWSLT SVETVQPAST EVETSQPAPM EAETSQPAPM EAETSQPAPM EAETSQPAPM EADTSQPAPM EAETSQPAPN EAETSKPAPT EAETSKPAPT EAETTQLPRI QAVKTLFTTS AATEVPSTEP TTMETASTES NESTIFLGPS VTHLPDSGLK KGLIVTPGNS PAPTLPGSSD LIPVKQC
• Sequence Length: 290

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Selplg recombinant protein

SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.

NCBI and Uniprot Product Information

• NCBI GI #: 341942014
• NCBI GeneID: 20345
• UniProt Accession #: Q62170
• Molecular Weight: 41,842 Da
• NCBI Official Full Name: P-selectin glycoprotein ligand 1
• NCBI Official Synonym Full Names: selectin, platelet (p-selectin) ligand
• NCBI Official Symbol: Selplg
• NCBI Official Synonym Symbols: CD162; Psgl1; Selp1; Selpl; Psgl-1
• NCBI Protein Information: P-selectin glycoprotein ligand 1
• UniProt Protein Name: P-selectin glycoprotein ligand 1
• Protein Family: P-selectin glycoprotein ligand
• UniProt Gene Name: Selplg
• UniProt Synonym Gene Names: Selp1; Selpl; PSGL-1

Uniprot Description

A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.