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741 results for "Akt inhibitor" - showing 50-100
Structure
PIK-93, Inhibitor (Cat# AAA576834)
Full Name
PIK-93
Purity
99.83%
Pricing
$195/2 mg | $230/5 mg | $280/10 mg | $420/25 mg | $230/1 mL (in DMSO) | $1,630/5x25 mg
SC66, Inhibitor (Cat# AAA578188)
Full Name
SC66
Purity
99.6%
Pricing
$195/5 mg | $210/10 mg | $245/25 mg | $300/50 mg | $1,070/5x50 mg
Structure
AS-605240, Inhibitor (Cat# AAA577366)
Full Name
AS-605240
Purity
97.0%
Pricing
$195/5 mg | $205/10 mg | $265/25 mg | $335/50 mg | $405/100 mg | $530/200 mg | $2,110/5x200 mg
p27Kip1 (T187), Blocking Peptide (Cat# AAA9225047)
Full Name
Phospho-p27Kip1(T187) Antibody Blocking peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Structure
KU55933, Inhibitor (Cat# AAA576517)
Full Name
KU55933
Purity
98.19%
Pricing
$195/5 mg | $210/10 mg | $245/25 mg | $300/50 mg | $400/100 mg | $200/1 mL (in DMSO) | $1,525/5x100 mg
Structure
AZD8055, Inhibitor (Cat# AAA575015)
Full Name
AZD8055
Purity
99.69%
Pricing
$200/5 mg | $205/10 mg | $225/25 mg | $235/50 mg | $290/100 mg | $395/200 mg | $200/1 mL (in DMSO) | $1,490/5x200 mg
Structure
BML-275, Inhibitor (Cat# AAA577477)
Full Name
BML-275
Purity
98.77%
Pricing
$205/5 mg | $230/10 mg | $325/25 mg | $385/50 mg | $605/100 mg | $825/200 mg | $3,450/5x200 mg
p27Kip1 (S178), Blocking Peptide (Cat# AAA9225045)
Full Name
Phospho-p27Kip1(S178) Antibody Blocking peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Structure
Tacrolimus, Inhibitor (Cat# AAA576529)
Full Name
Tacrolimus (FK506)
Purity
99.94%
Pricing
$195/10 mg | $205/25 mg | $215/50 mg | $245/100 mg | $370/500 mg | $285/200 mg | $1,400/5x500 mg
Testing Data
(Gefitinib (Iressa) is a novel potent EGFR tyrosine kinase and Akt phosphorylations inhibitor with IC50 of 37, 26 and 57 nM for Tyr1173, Tyr1173 and Tyr992 in, respectively, the low and high EGFR expressing cell lines. Immunoblot analysis of whole cell lysates revealed that in general gefitinib effectively inhibited all tyrosine phosphorylation sites on EGFR in both the high and low-EGFR-expressing cell lines. However, the phosphorylation sites Tyr1173 and Tyr992 were less sensitive requiring higher concentrations of gefitinib for inhibition. As was the case for ERK, gefitinib fails to effectively inhibit AKT phosphorylation in the high-EGFR- expressing cell line indicating that EGFR is not the major activator of AKT in this cell line. The low IC50 (7 nM), however show that the weak induction of AKT phosphorylation by EGFR in this cell line is efficiently blocked by gefitinib. Gefitinib inhibits AKT phosphorylations, with IC50 values of 220 and 263 nM, in the low-EGFR- and -EGFRvIII-expressing cell lines, respectively. [1] MCF10A cells are nontransformed breast epithelial cells that require EGF to proliferate.)
Gefitinib, Inhibitor (Cat# AAA8506564)
Full Name
Gefitinib (Iressa)
Purity
>99%
Pricing
$295/1 g | $1,255/5x1 g
p27Kip1, Blocking Peptide (Cat# AAA9228769)
Full Name
p27Kip1 Blocking Peptide (N-term S12)
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
CDKN1B-Y88, Blocking Peptide (Cat# AAA9229354)
Full Name
CDKN1B-Y88 Blocking Peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Structure
INK 128, Inhibitor (Cat# AAA576778)
Full Name
INK 128 (MLN0128)
Purity
98.0%
Pricing
$205/2 mg | $225/5 mg | $245/10 mg | $315/25 mg | $385/50 mg | $225/1 mL (in DMSO) | $1,470/5x50 mg
Structure
CNX-1351, Inhibitor (Cat# AAA575736)
Full Name
CNX-1351
Purity
99.7%
Pricing
$225/2 mg | $250/5 mg | $335/10 mg | $545/25 mg | $790/50 mg | $275/1 mL (in DMSO) | $3,280/5x50 mg
p27Kip1 (T198), Blocking Peptide (Cat# AAA9225172)
Full Name
Phospho-p27Kip1(T198) Antibody Blocking peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
p27Kip1, Blocking Peptide (Cat# AAA9228968)
Full Name
Mouse p27Kip1 Blocking Peptide (C-term T197)
Gene Names
Cdkn1b; p27; Kip1; p27Kip1; AA408329; AI843786
Structure
AZD2858, Inhibitor (Cat# AAA575112)
Full Name
AZD2858
Purity
99.3%
Pricing
$195/2 mg | $215/5 mg | $245/10 mg | $335/25 mg | $505/50 mg | $860/100 mg | $250/1 mL (in DMSO) | $3,605/5x100 mg
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human colon, using p27 KIP 1 Antibody(MBS179161)CDKN1B was detected in paraffin-embedded tissue section. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-CDKN1B Antibody (MBS179161)overnight at 4 degree C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37 degree C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen. )
p27 KIP 1, Monoclonal Antibody (Cat# AAA179161)
Full Name
Anti-p27 KIP 1 Rabbit Monoclonal Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human, Rat
Applications
FC/FACS, IP, IF, IHC, ICC, WB
Purity
Affinity-chromatography
Pricing
$370/0.1 mL | $1,600/5x0.1 mL
p27Kip1 (S10), Blocking Peptide (Cat# AAA9225044)
Full Name
Phospho-p27Kip1(S10) Antibody Blocking peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Cdkn1b, Blocking Peptide (Cat# AAA9223606)
Full Name
Mouse Cdkn1b Antibody (N-term) Blocking Peptide
Gene Names
Cdkn1b; p27; Kip1; p27Kip1; AA408329; AI843786
Testing Data
(PHT-427 is a dual Akt and PDPK1 inhibitor that affects downstream targetsamong sensitive but not resistant cells and tumor xenografts. When given orally, PHT-427 inhibited the growth of human tumor xenografts in immunodeficient mice, with up to 80% inhibition in the most sensitive tumors, and showed greater activity than analogues with C4, C6, or C8 alkyl chains. Inhibition of PDPK1 was more closely correlated to antitumor activity than Akt inhibition. [1])
PHT-427, Inhibitor (Cat# AAA8506159)
Full Name
PHT-427
Purity
>99%
Pricing
$295/10 mg | $1,255/5x10 mg
p27Kip1 (S140), Blocking Peptide (Cat# AAA9230831)
Full Name
Phospho-p27Kip1(S140) Blocking Peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
p27Kip1 (T170), Blocking Peptide (Cat# AAA9230834)
Full Name
Phospho-p27Kip1(T170) Blocking Peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Structure
IC-87114, Inhibitor (Cat# AAA575109)
Full Name
IC-87114 (IC87114)
Purity
95.58%
Pricing
$210/5 mg | $235/10 mg | $305/25 mg | $385/50 mg | $545/100 mg | $705/200 mg | $2,910/5x200 mg
Structure
Everolimus, Inhibitor (Cat# AAA576214)
Full Name
Everolimus (RAD001)
Purity
99.00%
Pricing
$195/5 mg | $200/10 mg | $225/25 mg | $245/50 mg | $265/100 mg | $315/200 mg | $200/1 mL (in DMSO) | $1,155/5x200 mg
p27Kip1 (T197), Blocking Peptide (Cat# AAA9230836)
Full Name
Phospho-mouse p27Kip1(T197) Blocking Peptide
Gene Names
Cdkn1b; p27; Kip1; p27Kip1; AA408329; AI843786
p27Kip1 (T157), Blocking Peptide (Cat# AAA9225046)
Full Name
Phospho-p27Kip1(T157) Antibody Blocking peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Structure
Methyl hesperidin, Inhibitor (Cat# AAA577375)
Full Name
Methyl hesperidin
Purity
98.7%
Pricing
$195/25 mg | $210/50 mg | $240/100 mg | $305/200 mg | $195/1 mL (in DMSO) | $1,105/5x200 mg
Structure
Apitolisib, Inhibitor (Cat# AAA576253)
Full Name
Apitolisib (GDC-0980, RG7422)
Purity
98.3%
Pricing
$195/2 mg | $205/5 mg | $230/10 mg | $305/25 mg | $535/100 mg | $210/1 mL (in DMSO) | $2,140/5x100 mg
Structure
XL147 analogue, Inhibitor (Cat# AAA575552)
Full Name
XL147 analogue
Purity
99.7%
Pricing
$195/2 mg | $210/5 mg | $230/10 mg | $275/25 mg | $355/50 mg | $505/100 mg | $620/200 mg | $235/1 mL (in DMSO) | $2,520/5x200 mg
Structure
MK-2206 2, Inhibitor (Cat# AAA577903)
Full Name
MK-2206 2 HCl
Purity
99.69%
Pricing
$185/2 mg | $200/5 mg | $215/10 mg | $265/25 mg | $290/50 mg | $350/100 mg | $505/200 mg | $200/1 mL (in DMSO) | $2,015/5x200 mg
Structure
Palomid 529 (P529), Inhibitor (Cat# AAA576985)
Full Name
Palomid 529 (P529)
Purity
98.6%
Pricing
$185/2 mg | $205/5 mg | $215/10 mg | $295/25 mg | $365/50 mg | $520/100 mg | $2,080/5x100 mg
Structure
SB216763, Inhibitor (Cat# AAA576051)
Full Name
SB216763
Purity
99.0%
Pricing
$180/2 mg | $200/5 mg | $215/10 mg | $270/25 mg | $330/50 mg | $465/100 mg | $200/1 mL (in DMSO) | $1,820/5x100 mg
Herbacetin, Inhibitor (Cat# AAA5750902)
Full Name
Herbacetin
Purity
96.89%
Pricing
$365/5 mg | $1,375/5x5 mg
Structure
BX795, Inhibitor (Cat# AAA577240)
Full Name
BX795
Purity
99.0%
Pricing
$205/5 mg | $240/10 mg | $340/25 mg | $475/50 mg | $650/100 mg | $225/1 mL (in DMSO) | $2,645/5x100 mg
Structure
Temsirolimus, Inhibitor (Cat# AAA576914)
Full Name
Temsirolimus (CCI-779, NSC 683864)
Purity
100.00%
Pricing
$205/5 mg | $235/10 mg | $315/25 mg | $445/50 mg | $615/100 mg | $865/200 mg | $245/1 mL (in DMSO) | $3,615/5x200 mg
Structure
CHIR-98014, Inhibitor (Cat# AAA575544)
Full Name
CHIR-98014
Purity
98.0%
Pricing
$200/2 mg | $240/5 mg | $310/10 mg | $400/25 mg | $635/50 mg | $885/100 mg | $245/1 mL (in DMSO) | $3,715/5x100 mg
Structure
AZ20, Inhibitor (Cat# AAA575299)
Full Name
AZ20
Purity
98.02%
Pricing
$180/2 mg | $205/5 mg | $225/10 mg | $280/25 mg | $375/50 mg | $205/1 mL (in DMSO) | $1,415/5x50 mg
Structure
IM-12, Inhibitor (Cat# AAA577237)
Full Name
IM-12
Purity
99.42%
Pricing
$195/1 mg | $205/5 mg | $225/10 mg | $295/25 mg | $640/100 mg | $840/200 mg | $205/1 mL (in DMSO) | $3,520/5x200 mg
Structure
Pilaralisib, Inhibitor (Cat# AAA577025)
Full Name
Pilaralisib (XL147)
Purity
99.6%
Pricing
$195/2 mg | $210/5 mg | $255/10 mg | $360/25 mg | $405/50 mg | $530/100 mg | $225/1 mL (in DMSO) | $2,110/5x100 mg
Structure
NU7026, Inhibitor (Cat# AAA577338)
Full Name
NU7026
Purity
100%
Pricing
$185/2 mg | $200/5 mg | $225/10 mg | $300/25 mg | $445/50 mg | $635/100 mg | $205/1 mL (in DMSO) | $2,600/5x100 mg
Structure
Acalisib, Inhibitor (Cat# AAA575469)
Full Name
Acalisib (GS-9820)
Purity
98.0%
Pricing
$195/2 mg | $230/5 mg | $270/10 mg | $360/25 mg | $465/50 mg | $620/100 mg | $230/1 mL (in DMSO) | $2,520/5x100 mg
Acacetin, Inhibitor (Cat# AAA579895)
Full Name
Acacetin
Purity
96.3%
Pricing
$195/5 mg | $205/10 mg | $230/25 mg | $195/1 mL (in DMSO) | $760/5x25 mg
p27Kip1 (S83), Blocking Peptide (Cat# AAA9230832)
Full Name
Phospho-p27Kip1(S83) Blocking Peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Structure
AT13148, Inhibitor (Cat# AAA578057)
Full Name
AT13148
Purity
97.0%
Pricing
$205/2 mg | $250/5 mg | $330/10 mg | $470/25 mg | $615/50 mg | $815/100 mg | $270/1 mL (in DMSO) | $3,405/5x100 mg
Structure
GDC-0032, Inhibitor (Cat# AAA576036)
Full Name
GDC-0032
Purity
99.6%
Pricing
$190/2 mg | $210/5 mg | $235/10 mg | $295/25 mg | $330/50 mg | $480/100 mg | $715/200 mg | $210/1 mL (in DMSO) | $2,945/5x200 mg
Structure
LY2584702, Inhibitor (Cat# AAA575500)
Full Name
LY2584702 tosylate
Purity
98.8%
Pricing
$195/2 mg | $220/5 mg | $265/10 mg | $350/25 mg | $490/50 mg | $675/100 mg | $245/1 mL (in DMSO) | $2,765/5x100 mg
Structure
Phenformin, Inhibitor (Cat# AAA575307)
Full Name
Phenformin HCl
Purity
99.17%
Pricing
$155/5 mg | $160/10 mg | $170/25 mg | $170/50 mg | $175/100 mg | $195/500 mg | $200/1 g | $185/200 mg | $630/5x1 g
TRIB3 / Tribbles Homolog 3, Recombinant Protein (Cat# AAA2903673)
Full Name
Human TRIB3 / Tribbles Homolog 3 Recombinant Protein
Gene Names
TRIB3; NIPK; SINK; TRB3; SKIP3; C20orf97
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Structure
Bikinin, Inhibitor (Cat# AAA576350)
Full Name
Bikinin
Purity
100.0%
Pricing
$200/5 mg | $205/10 mg | $230/25 mg | $275/50 mg | $365/100 mg | $555/200 mg | $200/1 mL (in DMSO) | $2,230/5x200 mg
