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22 results for "glucose metabolism inhibitor" - showing 1-22
Activity Data
(Figure. Cell proliferation of A549 cells after stimulated with GREM1.Gremlin (GREM1) is an inhibitor in the TGF beta signaling pathway. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. A proliferation assay was conducted to detect the bioactivity of recombinant mouse GREM1 using A549 cells. Briefly, A549 cells were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well and allowed to attach, replaced with serum-free overnight, then the medium was replaced with 2% serum standard DMEM prior to the addition of various concentrations of GREM1. After incubated for 96h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly,10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37 degree C. Proliferation of A549 cells after incubation with GREM1 for 96h observed by inverted microscope was shown in Figure1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8) assay after incubation with recombinant GREM1 for 96h. The result was shown in Figure 2. It was obvious that GREM1 significantly increased cell viability of A549 cells.(A) A549 cells cultured in DMEM, stimulated with 1ng/mL GREM1 for 96h; (B) Unstimulated A549 cells cultured in DMEM for 96h.)
Gremlin 1 (GREM1), Active Protein (Cat# AAA2105166)
Full Name
Active Gremlin 1 (GREM1)
Gene Names
Grem1; ld; Drm; Grem; Cktsf1b1
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$205/0.01 mg | $405/0.05 mg | $625/0.1 mg | $770/0.2 mg | $1,495/0.5 mg | $2,225/1 mg | $5,435/5 mg
Activity Data
(Figure. Cell proliferation of A549 cells after stimulated with GREM1.Gremlin (GREM1) is an inhibitor in the TGF beta signaling pathway. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. A proliferation assay was conducted to detect the bioactivity of recombinant human GREM1 using A549 cells. Briefly, A549 cells were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well and allowed to attach, replaced with serum-free overnight, then the medium was replaced with 2% serum standard DMEM prior to the addition of various concentrations of GREM1. After incubated for 96h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37 degree C. Proliferation of A549 cells after incubation with GREM1 for 96h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8) assay after incubation with recombinant GREM1 for 96h. The result was shown in Figure 2. It was obvious that GREM1 significantly increased cell viability of A549 cells.(A) A549 cells cultured in DMEM, stimulated with 1ng/mL GREM1 for 96h; (B) Unstimulated A549 cells cultured in DMEM for 96h.)
Gremlin 1 (GREM1), Active Protein (Cat# AAA2105165)
Full Name
Active Gremlin 1 (GREM1)
Gene Names
GREM1; DRM; HMPS; MPSH; PIG2; CRAC1; CRCS4; DAND2; HMPS1; IHG-2; DUP15q; C15DUPq; GREMLIN; CKTSF1B1
Applications
Cell Culture, Activity Assays
Purity
> 97%
Pricing
$195/0.01 mg | $390/0.05 mg | $600/0.1 mg | $735/0.2 mg | $1,425/0.5 mg | $2,120/1 mg | $5,215/5 mg
Testing Data
(Genistin(Genistoside) is an isoflavone found in a number of dietary plants like soy and kudzu.When ingested along the diet, genistin is readily converted to its aglycone form, genistein. It is hydrolyzed by removing the covalently bound glucose to form genistein and that genistein is the form of the compound that is absorbed in the intestine and is the form responsible for the biological activities of the isoflavone. [1])
Genistin, Inhibitor (Cat# AAA8506424)
Full Name
Genistin (Genistoside)
Purity
>99%
Pricing
$295/25 mg | $1,255/5x25 mg
Testing Data
(Phlorizin (Phloridzin) is a toxic 2'-glucoside of phloretin. It belongs to the group of dihydrochalcones, a type of flavonoids. It is a competitive inhibitor of renal glucose transport. Phlorizin is naturally occurring in some plants. It could be found in the bark of pear (Pyrus communis), apple, cherry and other fruit trees (Rosaceae) and is responsible for the petal color in Dianthus caryophyllus.)
Phlorizin, Inhibitor (Cat# AAA8506239)
Full Name
Phlorizin (Phloridzin)
Purity
>99%
Pricing
$210/500 mg | $910/5x500 mg
Testing Data
Dextrose, Inhibitor (Cat# AAA8506528)
Full Name
Dextrose (D-glucose)
Pricing
$295/10 mg | $1,255/5x10 mg
GLP-1, Inhibitor (Cat# AAA579898)
Full Name
GLP-1 (7-36)
Purity
98.0%
Pricing
$310/1 mg | $445/2 mg | $730/5 mg | $975/10 mg | $2,250/50 mg | $9,855/5x50 mg
1,2,3,4,6-O-Pentagalloylglucose, Inhibitor (Cat# AAA579770)
Full Name
1,2,3,4,6-O-Pentagalloylglucose
Purity
99.2%
Pricing
$185/2 mg | $200/5 mg | $215/10 mg | $290/25 mg | $1,030/5x25 mg
Cimiracemoside C, Inhibitor (Cat# AAA5760235)
Full Name
Cimiracemoside C
Purity
98.00%
Pricing
$235/1 mg | $315/5 mg | $425/10 mg | $680/25 mg | $955/50 mg | $1,370/100 mg | $5,895/5x100 mg
Structure
GPR120-IN-1, Inhibitor (Cat# AAA5754917)
Full Name
GPR120-IN-1
Purity
98.00%
Pricing
$220/2 mg | $245/5 mg | $315/10 mg | $485/25 mg | $690/50 mg | $1,065/100 mg | $240/1mL*10mM (in DMSO) | $4,505/5x100 mg
2-Hydroxy-1-Methoxyaporphine, Inhibitor (Cat# AAA5759959)
Full Name
2-Hydroxy-1-Methoxyaporphine
Purity
98.00%
Pricing
$460/5 mg | $1,785/5x5 mg
Structure
MK-0941, Inhibitor (Cat# AAA5753489)
Full Name
MK-0941 free base
Purity
98.00%
Pricing
$270/1 mg | $415/5 mg | $565/10 mg | $915/25 mg | $1,305/50 mg | $1,895/100 mg | $8,260/5x100 mg
Structure
Indeglitazar, Inhibitor (Cat# AAA5754995)
Full Name
Indeglitazar
Purity
98.00%
Pricing
$230/1 mg | $275/5 mg | $310/10 mg | $450/25 mg | $615/50 mg | $850/100 mg | $250/1mL*10mM (in DMSO) | $3,540/5x100 mg
Fagomine, Inhibitor (Cat# AAA5764546)
Full Name
Fagomine
Purity
98.00%
Pricing
$315/1 mg | $1,115/5x1 mg
Structure
CPDA, Inhibitor (Cat# AAA5752950)
Full Name
CPDA
Purity
98.00%
Pricing
$265/5 mg | $330/10 mg | $820/50 mg | $1,145/100 mg | $280/1mL*10mM (in DMSO) | $4,850/5x100 mg
Structure
Fasentin, Inhibitor (Cat# AAA5759401)
Full Name
Fasentin
Purity
98.00%
Pricing
$215/2 mg | $240/5 mg | $290/10 mg | $390/25 mg | $525/50 mg | $725/100 mg | $2,985/5x100 mg
Chemical Structure
Arhalofenate, Inhibitor (Cat# AAA5764685)
Full Name
Arhalofenate
Purity
0.9962
Pricing
$270/1 mg | $415/5 mg | $565/10 mg | $915/25 mg | $1,305/50 mg | $1,895/100 mg | $8,260/5x100 mg
Structure
3-Guanidinopropionic Acid, Inhibitor (Cat# AAA5758423)
Full Name
3-Guanidinopropionic Acid
Purity
98.00%
Pricing
$195/5 mg | $615/5x5 mg
Structure
Nepodin, Inhibitor (Cat# AAA5759850)
Full Name
Nepodin
Purity
98.00%
Pricing
$440/5 mg | $665/10 mg | $2,725/5x10 mg
Chemical Structure
2-Deoxy-D-glucose, Inhibitor (Cat# AAA3841706)
Full Name
2-Deoxy-D-glucose
Purity
>98%
Pricing
$125/500 mg | $515/5x500 mg
Structure
Fucosterol, Inhibitor (Cat# AAA5759005)
Full Name
Fucosterol
Purity
99.68%
Pricing
$225/5 mg | $275/10 mg | $960/5x10 mg
AMG-3969, Inhibitor (Cat# AAA5764313)
Full Name
AMG-3969
Purity
98.00%
Pricing
$270/1 mg | $445/5 mg | $605/10 mg | $1,045/25 mg | $1,500/50 mg | $2,115/100 mg | $3,095/200 mg | $615/1 mL (in DMSO) | $13,655/5x200 mg
Conduritol B epoxide, Inhibitor (Cat# AAA5764548)
Full Name
Conduritol B epoxide
Purity
98.00%
Pricing
$205/5 mg | $230/10 mg | $270/25 mg | $340/50 mg | $405/100 mg | $500/200 mg | $210/1 mL (in DMSO) | $1,975/5x200 mg
