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105 results for "PKA inhibitor" - showing 1-50
Testing Data
DARPP-32 (Thr34), Polyclonal Antibody (Cat# AAA502018)
Full Name
Anti-Phospho-Thr34 DARPP-32
Gene Names
Ppp1r1b; Darpp32; Darpp-32
Reactivity
Rat
Applications
WB
Purity
Affinity Purified (Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.)
Pricing
$420/0.1 mL | $1,740/5x0.1 mL
Testing Data
DARPP-32 (Ser137), Polyclonal Antibody (Cat# AAA502169)
Full Name
Anti-Phospho-Ser137 DARPP-32
Gene Names
Ppp1r1b; Darpp32; Darpp-32
Reactivity
Rat
Applications
WB
Purity
Affinity Purified (Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.)
Pricing
$420/0.1 mL | $1,740/5x0.1 mL
Testing Data
DARPP-32 (Thr75), Polyclonal Antibody (Cat# AAA502019)
Full Name
Anti-Phospho-ThrDARPP-32
Gene Names
Ppp1r1b; Darpp32; Darpp-32
Reactivity
Rat
Applications
WB
Purity
Affinity Purified (Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.)
Pricing
$420/0.1 mL | $1,740/5x0.1 mL
Testing Data
DARPP-32, Polyclonal Antibody (Cat# AAA502017)
Full Name
Anti-DARPP-32
Gene Names
Ppp1r1b; Darpp32; Darpp-32
Reactivity
Rat
Applications
WB, IHC
Purity
Affinity Purified (Prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the N-terminal peptide used as antigen.)
Pricing
$420/0.1 mL | $1,740/5x0.1 mL
Western Blot (WB)
(Western Blotting Lysates prepared from 3T3-L1 cells (1-4) or COS cells overexpressing WT AS160 (5, 6) or mutant AS160 T642A, treated with PI-3-Kinase inhibitor(5), insulin (1-4, 6-7), were resolved by SDS-PAGE on a 10% polyacrylamide gel and transferred to PVDF. Membrane was blocked with a 5% BSA-TBST buffer for one hour at room temperature, and incubated with MBS614987 for two hours at room temperature in 3% BSA-TBST buffer, following prior incubation with: no peptide (1, 5-7), the non-phosphopeptide corresponding to the immunogen (2), a generic phosphothreonine-containing peptide (3) the phosphopeptide immunogen (4). After washing, membranes were incubated with goat F(ab’)2 anti-rabbit IgG HRP conjugate and bands were detected using the Pierce SuperSignal™ method. The data show that only the phosphopeptide corresponding to AS160 blocks the signal. The data also show that the signal was blocked in cells overexpressing site-directed mutant T642A, indicating the antibody is phosphorylation site specific.)
Akt Substrate, 160kD, Polyclonal Antibody (Cat# AAA614987)
Full Name
Akt Substrate, 160kD, phosphorylated (Thr642) (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)
Gene Names
Akt1; akt; Akt; AKT; Akt/PKB; AKT/PKB; akt1; AKT1; Akt1|PKB; CG4006; D-Akt; dakt; dAkt; dAKT; Dakt; DAkt; dAKT/dPKB; dAkt/PKB; dakt1; dAkt1; dAKT1; Dakt1; DAkt1; DAKT1; DAKT1/PKB; DmelCG4006; dPKB; Dpkb; DPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq;
Reactivity
Human
Applications
EL/EIA, WB
Purity
Affinity Purified
Purified from rabbit serum by affinity chromatography.
Purified from rabbit serum by affinity chromatography.
Pricing
$715/10 Blots | $3,205/5x10 Blots
Western Blot (WB)
(Western Blot analysis of extracts from rat brain cortex, untreated or phosphorylated in vitro by PKA, MAP kinase or cdc2 kinase, using MBS618248 (top), Phospho-DARPP-32 (Thr34) Antibody D1075-03 (middle) or D1075-01(bottom).)
DARPP32, Polyclonal Antibody (Cat# AAA618248)
Full Name
DARPP32, phosphorylated (Thr75) (Dopamine and cAMP-regulated Phosphoprotein, Protein phosphatase 1 regulatory subunit 1B, PP1R1B)
Gene Names
PPP1R1B; DARPP32; DARPP-32
Reactivity
Mouse, Rat
Applications
EL/EIA, WB
Purity
Affinity Purified
Purified by Protein A and immunoaffinity chromatography.
Purified by Protein A and immunoaffinity chromatography.
Pricing
$660/0.1 mL | $2,955/5x0.1 mL
Western Blot (WB)
(Western Blot analysis of A431 cells, untreated or calyculin A-treated, using MBS627817.)
Protein Kinase A, Substrate, Polyclonal Antibody (Cat# AAA627817)
Full Name
Protein Kinase A, Substrate, Phosphorylated (Ser/Thr) (PKA)
Applications
EL/EIA, WB, IP, IHC
Purity
Affinity Purified
Purified by protein A and peptide affinity chromatography.
Purified by protein A and peptide affinity chromatography.
Pricing
$660/0.1 mL | $2,955/5x0.1 mL
K252a, Inhibitor (Cat# AAA655447)
Full Name
K252a
Purity
Highly Purified
~98%
~98%
Pricing
$495/0.1 mg | $2,220/5x0.1 mg
SDS-Page
(Peptide Competition and Phosphatase Treatment Lysates prepared from NIH3T3 cells stimulated with PDGF were resolved by SDS-PAGE on a 10% polyacrylamide gel and transferred to PVDF. Membranes were either left untreated (1-5) or treated with lambda (λ) phosphatase (6), blocked with a 5% BSA-TBST buffer for one hour at room temperature, and incubated with MBS625189for two hours at room temperature in a 3% BSA-TBST buffer, following prior incubation with: no peptide (1, 2, 6), the non-phosphopeptide corresponding to the immunogen (3), a generic phosphoserine-containing peptide (4), or, the phosphopeptide immunogen (5). After washing, membranes were incubated with goat F(ab’)2 anti-rabbit IgG HRP conjugate and bands were detected using the Pierce SuperSignal‘ method. The data show that the peptide corresponding to CREB [pSpS129/133] blocks the antibody signal. The data also show that phosphatase stripping eliminates the signal, verifying that the antibody is phospho-specific. Pretreatment of cells with PKA inhibitor (PKI) or GSK-3 β inhibitor (LiCl) diminished the signal, indicating the dual phosphoreactivity of this antibody (data not shown).)
CREB, Polyclonal Antibody (Cat# AAA625189)
Full Name
CREB, phosphorylated (Ser129, Ser133) (cAMP Response Element Binding Protein)
Gene Names
CREB1; CREB; MGC9284
Reactivity
Human, Mouse
Applications
EL/EIA, WB
Purity
Affinity Purified
Purified from rabbit serum by sequential epitope-specific chromatography. Negatively preadsorbed using a non-phosphopeptide corresponding to the site of phosphorylation to remove antibody that is reactive with non-phosphorylated CREB.
Purified from rabbit serum by sequential epitope-specific chromatography. Negatively preadsorbed using a non-phosphopeptide corresponding to the site of phosphorylation to remove antibody that is reactive with non-phosphorylated CREB.
Pricing
$875/0.1 mL | $3,920/5x0.1 mL
Structure
Baricitinib, Inhibitor (Cat# AAA576687)
Full Name
Baricitinib (LY3009104, INCB028050)
Purity
98.9%
Pricing
$185/2 mg | $195/5 mg | $205/10 mg | $230/25 mg | $245/50 mg | $270/100 mg | $195/1 mL (in DMSO) | $950/5x100 mg
Western Blot (WB)
(Western Blot analysis of extracts from PDGF, wortmannin and LY294002 treated NIH/3T3 cells, using A1124-02 (A); A1124-92 (B) or A1124-03 (C). D is an analysis of Akt activity in PDGF,wortmannin and LY294002 treated NIH/3T3 cells, using Akt Kinase (Rac PKa, PKBa) Assay Kit BioAssay™ (A1125-45).)
LY294002, Inhibitor (Cat# AAA655326)
Full Name
LY294002 (PI 3 Kinase Inhibitor, 2-(4-Morpholinyl)-8-phenyl-4H-1- benzopyran-4-one)
Pricing
$360/0.5 mg | $1,620/5x0.5 mg
Western Blot (WB)
(Western blot of rat caudate lysate showing specific immunolabeling of ~32k DARPP-32 phosphorylated at Thr137 (Control))
PPP1R1B, Polyclonal Antibody (Cat# AAA835413)
Full Name
PPP1R1B antibody (Ser137)
Gene Names
PPP1R1B; DARPP32; DARPP-32
Applications
WB
Purity
PPP1R1B antibody was purified by affinity chromatography
Pricing
$640/0.1 mL | $2,870/5x0.1 mL
Western Blot (WB)
(Western blot of rat caudate lysate showing specific immunolabeling of ~32k DARPP-32 phosphorylated at Thr75 (Control))
PPP1R1B, Polyclonal Antibody (Cat# AAA835057)
Full Name
PPP1R1B antibody (Thr75)
Gene Names
Ppp1r1b; Darpp32; Darpp-32
Applications
WB
Purity
PPP1R1B antibody was purified by affinity chromatography
Pricing
$640/0.1 mL | $2,870/5x0.1 mL
Protein Kinase A, Inhibitor Peptide, Inhibitor (Cat# AAA655454)
Full Name
Protein Kinase A, Inhibitor Peptide (TYADFIASGRTGRRNAI-NH2) (PKA)
Purity
Highly Purified
90% as determined by HPLC
90% as determined by HPLC
Pricing
$710/2 mg | $3,190/5x2 mg
Molecular Structure
AG-1478, Inhibitor (Cat# AAA515019)
Full Name
AG-1478
Purity
>98% (TLC); NMR (Conforms)
Pricing
$225/5 mg | $515/25 mg | $2,105/5x25 mg
H-89 2HCl, Inhibitor (Cat# AAA515005)
Full Name
H-89 2HCl
Pricing
$215/5 mg | $465/25 mg | $1,865/5x25 mg
SDS-Page
(SDS-PAGE: 10ug of Raf-1, active.)
Raf1, Truncated, active, Active Protein (Cat# AAA637844)
Full Name
Raf1, Truncated, active, Recombinant, Human
Purity
Highly Purified
~70%
~70%
Pricing
$995/0.01 mg | $4,470/5x0.01 mg
Protein Kinase Inhibitor H-9, Biochemical (Cat# AAA6113585)
Full Name
Protein Kinase Inhibitor H-9 (PKI) (N-(2-aminoethyl)-5-isoquinolinesulfonamide dihydrochloride)
Purity
Molecular Biology Grade
>98%
Applications:
Suitable for use in inhibition of PKA (Ki=1.9 um), PKC (Ki=18 uM), PKG (Ki=870 nM). Useful as a ligand for separation and purification of these three enzymes.. Other applications not tested.
>98%
Applications:
Suitable for use in inhibition of PKA (Ki=1.9 um), PKC (Ki=18 uM), PKG (Ki=870 nM). Useful as a ligand for separation and purification of these three enzymes.. Other applications not tested.
Pricing
$565/25 mg | $2,535/5x25 mg
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells using IPKA antibody)
IPKA, Polyclonal Antibody (Cat# AAA5300312)
Full Name
IPKA antibody
Reactivity
Reactivity: Human. Cross Reactivity: Mouse, Rat
Applications
IHC, IF, EIA
Pricing
$405/0.1 mg | $1,805/5x0.1 mg
Structure
MLN8054, Inhibitor (Cat# AAA578869)
Full Name
MLN8054
Purity
98.3%
Pricing
$215/2 mg | $240/5 mg | $310/10 mg | $445/25 mg | $740/50 mg | $1,030/100 mg | $240/1 mL (in DMSO) | $4,375/5x100 mg
PKIB, Polyclonal Antibody (Cat# AAA5303198)
Full Name
PKIB antibody
Gene Names
Pkib; Pkibeta; Prkacn2
Applications
EIA, IHC
Purity
PKIB antibody was purified by Antigen Affinity chromatography
Pricing
$400/0.05 mL | $1,780/5x0.05 mL
Chemical Structure
(Chemical structure of H89 Dihydrochloride (SIH-452), a PKA inhibitor. CAS #: 127243-85-0. Molecular Formula: C20H22BrCl2N3O2S. Molecular Weight: 519.3 g/mol.)
H89, Small Molecule (Cat# AAA808152)
Full Name
H89 Dihydrochloride
Purity
99% (TLC)
Pricing
$215/5 mg | $480/25 mg | $1,925/5x25 mg | $735/5x5 mg
Chemical Structure
(Chemical structure of KT5720 (SIH-457), a PKA kinase inhibitor. CAS #: 108068-98-0. Molecular Formula: C32H31N3O5. Molecular Weight: 537.6 g/mol.)
KT5720, Small Molecule (Cat# AAA808157)
Full Name
KT5720
Purity
>=98% (TLC)
Pricing
$250/0.1 mg | $600/0.5 mg | $905/5x0.1 mg | $2,470/5x0.5 mg
Structure
PKA Inhibitor Substrate, Peptide (Cat# AAA8246934)
Full Name
PKA Inhibitor Substrate
Purity
> 95%
Pricing
$290/1 mg | $610/5 mg | $875/10 mg | $3,880/5x10 mg
Structure
H 89, Inhibitor (Cat# AAA578813)
Full Name
H 89 diHydrochloride
Purity
99.38%
Pricing
$205/10 mg | $265/25 mg | $350/50 mg | $520/100 mg | $750/200 mg | $200/1 mL (in DMSO) | $3,100/5x200 mg
Chemical Structure
A-674563, Inhibitor (Cat# AAA5750558)
Full Name
A-674563 HCl (552325-73-2(Free Base))
Purity
98.0%
Pricing
$225/1 mg | $250/2 mg | $280/5 mg | $330/10 mg | $470/25 mg | $640/50 mg | $895/100 mg | $280/1mL*10mM (in DMSO) | $3,745/5x100 mg
ML281, Inhibitor (Cat# AAA579563)
Full Name
ML281
Purity
99.7%
Pricing
$195/2 mg | $225/5 mg | $245/10 mg | $340/25 mg | $510/50 mg | $760/100 mg | $1,150/200 mg | $230/1 mL (in DMSO) | $4,900/5x200 mg
YWHAZ / 14-3-3 Protein Zeta/Delta, Recombinant Protein (Cat# AAA2902541)
Full Name
Human YWHAZ / 14-3-3 Protein Zeta/Delta Recombinant Protein
Gene Names
YWHAZ; HEL4; YWHAD; KCIP-1; HEL-S-3; POPCHAS; HEL-S-93; 14-3-3-zeta
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
CCG215022, Inhibitor (Cat# AAA579628)
Full Name
CCG215022
Purity
99.7%
Pricing
$265/1 mg | $330/2 mg | $475/5 mg | $630/10 mg | $1,080/25 mg | $1,525/50 mg | $2,090/100 mg | $475/1 mL (in DMSO) | $9,130/5x100 mg
GSK180736A, Inhibitor (Cat# AAA579642)
Full Name
GSK180736A
Purity
98.4%
Pricing
$205/2 mg | $215/5 mg | $235/10 mg | $305/25 mg | $440/50 mg | $705/100 mg | $215/1 mL (in DMSO) | $2,905/5x100 mg
GALNON TFA, Inhibitor (Cat# AAA5759345)
Full Name
GALNON TFA (475115-35-6(free base))
Purity
98.00%
Pricing
$270/1 mg | $415/5 mg | $565/10 mg | $915/25 mg | $3,845/5x25 mg
PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A, Recombinant Protein (Cat# AAA2902927)
Full Name
Human PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A Recombinant Protein
Gene Names
PPP1R1A; I1; IPP1
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
MYPT1, Polyclonal Antibody (Cat# AAA9613797)
Full Name
MYPT1 Antibody
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Mouse, Rat
Applications
EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Structure
TBBD, Inhibitor (Cat# AAA3604589)
Full Name
TBBD
Purity
>98% (HPLC)
Pricing
$185/10 mg | $190/25 mg | $210/50 mg | $235/100 mg | $265/200 mg | $915/5x200 mg
Structure
Erismodegib diphosphate, Inhibitor (Cat# AAA5755083)
Full Name
Erismodegib diphosphate
Purity
99.86%
Pricing
$200/5 mg | $205/10 mg | $240/25 mg | $255/50 mg | $330/100 mg | $215/1 mL (in DMSO) | $1,215/5x100 mg
S107, Inhibitor (Cat# AAA579572)
Full Name
S107
Purity
99.6%
Pricing
$205/2 mg | $240/5 mg | $290/10 mg | $390/25 mg | $565/50 mg | $775/100 mg | $245/1 mL (in DMSO) | $3,230/5x100 mg
Myristoylated AIP, Peptide (Cat# AAA566459)
Full Name
Myristoylated AIP
Purity
>=95% (HPLC)
Pricing
$235/0.5 mg | $1,005/5x0.5 mg
Western Blot (WB)
(Western blot analysis of extracts from A549 cells, using Phospho-MYPT1 (Ser473) Antibody. The lane on the left was treated with blocking peptide.Observed bands: 150kDa)
MYPT1, Polyclonal Antibody (Cat# AAA9612844)
Full Name
Phospho-MYPT1 (Ser473) Antibody
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
MYPT1, Polyclonal Antibody (Cat# AAA9613800)
Full Name
MYPT1 Antibody
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Mouse, Rat
Applications
EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunofluorescence (IF)/Immunocytochemistry (ICC)
(Staining Hela cells(heat shock treatment) by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25 degree C. Samples were then incubated with primary Ab(AF3775) and mouse anti-beta tubulin Ab(T0023) for 1 hour at 37 degree C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody.The nuclear counter stain is DAPI (blue).)
MYPT1, Polyclonal Antibody (Cat# AAA9612843)
Full Name
Phospho-MYPT1 (Ser852) Antibody
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Mouse, Rat
Applications
IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Structure
Daphnetin, Inhibitor (Cat# AAA3604626)
Full Name
Daphnetin
Purity
>98% (HPLC)
Pricing
$190/10 mg | $235/25 mg | $390/100 mg | $520/200 mg | $2,070/5x200 mg
Western Blot (WB)
(Western blot analysis of extracts from serum starvation treated P19 cells, using MYPT1 Antibody. The lane on the left was treated with blocking peptide.Observed bands: 140kDa)
MYPT1, Polyclonal Antibody (Cat# AAA9613796)
Full Name
MYPT1 Antibody
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Isopedicin, Inhibitor (Cat# AAA5762600)
Full Name
Isopedicin
Purity
98.00%
Pricing
$380/1 mg | $1,425/5x1 mg
H-89 PKA, Inhibitor (Cat# AAA8579815)
Full Name
H-89 PKA Inhibitor
Purity
99% (TLC: 10% Methanol/methylene chloride; Rf = 0.65)
Pricing
$140/1 mg | $575/5x1 mg
Structure
Ro-3306, Inhibitor (Cat# AAA3606340)
Full Name
Ro-3306
Purity
>98% (HPLC)
Pricing
$190/2 mg | $210/5 mg | $230/10 mg | $290/25 mg | $370/50 mg | $530/100 mg | $845/200 mg | $3,505/5x200 mg
Structure
A-674563, Inhibitor (Cat# AAA3604998)
Full Name
A-674563
Purity
>98% (HPLC)
Pricing
$240/2 mg | $265/5 mg | $335/10 mg | $585/25 mg | $730/50 mg | $3,015/5x50 mg
Structure
GSK-180736A, Inhibitor (Cat# AAA3606040)
Full Name
GSK-180736A
Purity
>98% (HPLC)
Pricing
$200/2 mg | $210/5 mg | $230/10 mg | $300/25 mg | $405/50 mg | $645/100 mg | $2,625/5x100 mg
Western Blot (WB)
(Western blot analysis of MYPT1 (Phospho-Ser472) using calyculin treated HeLa whole cell lysates.-/+ means absence or presence of N peptide（non-phospho peptide) and P peptide(phospho peptide).)
MYPT1, Polyclonal Antibody (Cat# AAA9612847)
Full Name
Phospho-MYPT1 (Ser472) Antibody
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB)
(Western blot analysis of MYPT1/2 (Phospho-Ser668/Ser618) using K562 whole cell lysates.-/+ means absence or presence of N peptide（non-phospho peptide) and P peptide(phospho peptide).)
MYPT1/2, Polyclonal Antibody (Cat# AAA9614443)
Full Name
Phospho-MYPT1/2 (Ser668/Ser618) Antibody
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Predicted Reactivity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Applications
WB, IHC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
alpha-Amyrin palmitate, Inhibitor (Cat# AAA5761855)
Full Name
alpha-Amyrin palmitate
Purity
98.00%
Pricing
$275/1 mg | $940/5x1 mg
