Filters
Clonality
Type
Reactivity
Gene Name
Isotype
Host
Application
Clone
2 results for " NIR FLIVO 747 Tracer In vivo Assay" - showing 1-2
Testing Data
(NON-INVASIVE IMAGING OF APOPTOSIS RESULTING FROM HSV-1 VIRAL INFECTION. Adult wild-type Balb/c mice were either inoculated with HSV-1 virus, which is known to induce apoptosis in the brain, or given a sham treatment. Seven days after viral inoculation, the mice were injected intravenously with either the NIR-FLIVO 747 Tracer to detect caspase activity, the NIR-FLIVO 747 Free Dye to detect where the dye reagent is getting trapped within tissues, or no reagent. The animals were then imaged with a Carestream In Vivo FX PRO imager seven hours after reagent injection. Strong caspase activity was located in the brain of the animal treated with HSV-1 and injected with NIR-FLIVO 747 Tracer (NIR-FLIVO 747 +). Minimal signal was detected in the liver region of the HSV-treated animal injected with the free dye control (HSV-treated; NIR 747 Free Dye +) and of the uninfected mouse injected with NIR-FLIVO 747 Tracer. The liver is the route of clearance for FLIVO Tracers. All mice show fluorescence signal in the tail where reagent is likely to pool after IV injection.)
NIR-FLIVO 747 Free Dye, Assay Kit (Cat# AAA258413)
Full Name
NIR-FLIVO 747 Free Dye Control Assay
Testing Data
(IN VIVO MONITORING OF APOPTOSIS DURING EXPERIMENTAL ANTI-CANCER TREATMENT. Apoptotic tissues in murine tumor models were imaged in vivo with NIR-FLIVO 747 Tracer (*Dylight 747-VAD-FMK) us¬ing the CRi Maestro imaging system. NIR-FLIVO 747 was used to non-invasively monitor the efficacy and time kinetics of an experimental anti-cancer treatment. After receiving a placebo or an experimental treatment, negative control mice (left image) and experimentally treated mice (right image) were injected intravenously with NIR-FLIVO 747 Tracer and imaged non-invasively at various time points with the CRi Maestro imaging system. Apoptotic tumor tissues fluoresce bright blue in the experimental group subjects, indicating that the experimental treatment had an apoptotic effect.)
NIR-FLIVO 747 Tracer, Assay Kit (Cat# AAA258412)
Full Name
NIR-FLIVO 747 Tracer In vivo Assay
