SDF1 recombinant protein
SDF1 protein (Mouse) (His tag)
Applications
ELISA, SDS-Page, Western Blot
Purity
> 90% pure
Synonyms
SDF1; SDF1 protein (Mouse) (His tag); 12 O tetradecanoylphorbol 13 acetate repressed 1 protein; TPAR1 protein; C X C motif chemokine 12 protein; Pre B cell growth stimulating factor protein; PBSF protein; Thymic lymphoma cell stimulating factor protein; TLSF protein; Stromal cell derived factor 1 protein; SDF 1 protein; SDF-1 protein; SDF1 recombinant protein
Host
Mouse
Purity/Purification
> 90% pure
Form/Format
Supplied in Tris-based buffer with 50% glycerol
Applicable Applications for SDF1 recombinant protein
ELISA (EIA), SDS-PAGE, Western Blot (WB)
Protein Type
Recombinant
Biological Significance
SDF1 is a chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. Stimulates the proliferation of bone marrow-derived b progenitor cells in the presence of IL-7 as well as growth of the stromal cell-dependent B-cell clone DW34 cells.
Expression System
E Coli
Tag/Conjugate
His tag
Preparation and Storage
Store at 4 degree C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 degree C, avoid repeat freeze/thaw cycles
Related Product Information for SDF1 recombinant protein
Purified recombinant SDF1 protein (Mouse) (His tag)
Product Categories/Family for SDF1 recombinant protein
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Product Notes
The SDF1 (Catalog #AAA5304507) is a Recombinant Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SDF1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the SDF1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SDF1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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