UPF0667 protein C1orf55 homolog Recombinant Protein | SDE2 recombinant protein
Recombinant Pongo abelii UPF0667 protein C1orf55 homolog
Gene Names
SDE2; C1orf55
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
UPF0667 protein C1orf55 homolog; Recombinant Pongo abelii UPF0667 protein C1orf55 homolog; SDE2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-451, Full length protein
Sequence
MAEAAALVWIRGPGFGCKAVRCASARCTVRDFIHRHCQDQNVPVENFFVKCNGALIYTSDTVQHGAVYSLEPRLCGGKGGFGSMLRALGAQIEKTTNREACRDLSGRRLRDVNHEKAMAEWVKQQAEREAEKEQKRLERLQRKLVEPKHCFTSPDYQQQCHEMAERLEDSVLKGMQAASSKMVSAEISENRKRQWPTKSQTDREASAGKRRYFWLGMEGLETAEGSSSESSDDDSEEAPSTSGMGFHAPKIGGSGVEMAAKFPSGSQRARVVNTDPGSPEQLQIPVTDSGRHISEDSCAELGESKEHMESRMVTETEETQEKKAESREPIEEEPTGAGLNKDKETEERTDGERVAEVACEERENVAVAKLQESQPGNAVIDKETIDLLAFTSVAELELLGLEKLKCELMALGLKCGGTLQERAARLFSVRGLAKEQIDPALFAKPLKGKKK
Sequence Length
451
Species
Pongo abelii (Sumatran orangutan)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,821 Da
NCBI Official Full Name
replication stress response regulator SDE2
NCBI Official Symbol
SDE2
NCBI Official Synonym Symbols
C1orf55
NCBI Protein Information
replication stress response regulator SDE2
UniProt Protein Name
Replication stress response regulator SDE2
Protein Family
UniProt Gene Name
SDE2
Uniprot Description
Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract damage due to ultraviolet light induced replication stress. The complete degradation of SDE2 is necessary to allow S-phase progression.
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Product Notes
The SDE2 sde2 (Catalog #AAA1373360) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-451, Full length protein. The amino acid sequence is listed below: MAEAAALVWI RGPGFGCKAV RCASARCTVR DFIHRHCQDQ NVPVENFFVK CNGALIYTSD TVQHGAVYSL EPRLCGGKGG FGSMLRALGA QIEKTTNREA CRDLSGRRLR DVNHEKAMAE WVKQQAEREA EKEQKRLERL QRKLVEPKHC FTSPDYQQQC HEMAERLEDS VLKGMQAASS KMVSAEISEN RKRQWPTKSQ TDREASAGKR RYFWLGMEGL ETAEGSSSES SDDDSEEAPS TSGMGFHAPK IGGSGVEMAA KFPSGSQRAR VVNTDPGSPE QLQIPVTDSG RHISEDSCAE LGESKEHMES RMVTETEETQ EKKAESREPI EEEPTGAGLN KDKETEERTD GERVAEVACE ERENVAVAKL QESQPGNAVI DKETIDLLAF TSVAELELLG LEKLKCELMA LGLKCGGTLQ ERAARLFSVR GLAKEQIDPA LFAKPLKGKK K. It is sometimes possible for the material contained within the vial of "UPF0667 protein C1orf55 homolog, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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