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SDS-Page (Figure 1. Human CD138, hFc-His Tag on SDS-PAGE under reducing condition.)

CD138 recombinant protein

Recombinant human CD138 protein with C-terminal human Fc and 6xHis tag

Gene Names
SDC1; SDC; CD138; SYND1; syndecan
Applications
Western Blot
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
CD138; Recombinant human CD138 protein with C-terminal human Fc and 6xHis tag; Human CD138 Protein; hFc-His Tag; SDC1; Syndecan-1; SYND1; SDC; CD138 recombinant protein
Ordering
For Research Use Only!
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-13% trehalose is added as protectants before lyophilization.
Sequence
CD138(Gln23-Gly254)+hFc(Glu99-Ala330)
Applicable Applications for CD138 recombinant protein
Western Blot (WB)
Source
Human
Conjugation
C-Human Fc and 6xHis tag
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice

SDS-Page

(Figure 1. Human CD138, hFc-His Tag on SDS-PAGE under reducing condition.)

SDS-Page (Figure 1. Human CD138, hFc-His Tag on SDS-PAGE under reducing condition.)
Related Product Information for CD138 recombinant protein
Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1/SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,462 Da
NCBI Official Full Name
syndecan-1
NCBI Official Synonym Full Names
syndecan 1
NCBI Official Symbol
SDC1
NCBI Official Synonym Symbols
SDC; CD138; SYND1; syndecan
NCBI Protein Information
syndecan-1; CD138 antigen; syndecan proteoglycan 1; heparan sulfate proteoglycan fibroblast growth factor receptor
UniProt Protein Name
Syndecan-1
UniProt Gene Name
SDC1
UniProt Synonym Gene Names
SDC; SYND1
UniProt Entry Name
SDC1_HUMAN

NCBI Description

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

Uniprot Description

syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family.

Protein type: Motility/polarity/chemotaxis; Extracellular matrix; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: lysosomal lumen; focal adhesion; cell surface; protein complex; Golgi lumen; integral to plasma membrane; cytoplasm; plasma membrane; external side of plasma membrane

Molecular Function: protein C-terminus binding; protein binding; glycoprotein binding

Biological Process: phototransduction, visible light; extracellular matrix organization and biogenesis; response to cAMP; myoblast development; wound healing; glycosaminoglycan metabolic process; striated muscle cell development; response to toxin; response to glucocorticoid stimulus; pathogenesis; lipoprotein metabolic process; Wnt receptor signaling pathway through beta-catenin; Sertoli cell development; odontogenesis; chondroitin sulfate metabolic process; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; response to hydrogen peroxide; ureteric bud development; carbohydrate metabolic process; inflammatory response; response to calcium ion; retinoid metabolic process

Research Articles on CD138

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Product Notes

The CD138 sdc1 (Catalog #AAA188062) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD138 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CD138 sdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: CD138(Gln2 3-Gly254)+ hFc(Glu99- Ala330). It is sometimes possible for the material contained within the vial of "CD138, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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