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Mammaglobin B/SCGB2A1 Recombinant Protein | SCGB2A1 recombinant protein

Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc Tag)

Gene Names
SCGB2A1; LPHC; LPNC; MGB2; UGB3
Purity
>95% as determined by SDS-PAGE
Synonyms
Mammaglobin B/SCGB2A1; Mammaglobin B/SCGB2A1 Protein; Human; Recombinant (hFc Tag); Human Mammaglobin-B/SCGB2A1 Protein (Fc Tag); LIPHC Protein; LPHC Protein; LPNC Protein; MGB2 Protein; UGB3 Protein; secretoglobin family 2A member 1; SCGB2A1 recombinant protein
Ordering
For Research Use Only!
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Asn95
Species
Human
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Asp 19
Tag
C-human IgG1-Fc
Protein Construction
A DNA sequence encoding the human SCGB2A1 (NP_002398.1)(Met1-Asn95) was expressed with the Fc region of human IgG1 at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.

SDS-Page

SDS-Page
Related Product Information for SCGB2A1 recombinant protein
Background: SCGB2A1 represented a novel, prognostic factor for CRC, and that expression of SCGB2A1 correlated with chemoresistance, radioresistance and cancer cell stemness. SCGB2A1 is a top differentially expressed gene in all major histological types of ovarian cancers and may represent a novel and attractive target for the immunotherapy of patients harbouring recurrent disease resistant to chemotherapy.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,884 Da
NCBI Official Full Name
mammaglobin-B
NCBI Official Synonym Full Names
secretoglobin, family 2A, member 1
NCBI Official Symbol
SCGB2A1
NCBI Official Synonym Symbols
LPHC; LPNC; MGB2; UGB3
NCBI Protein Information
mammaglobin-B; lacryglobin; lipophilin C; lipophilin-C; mammaglobin 2; mammaglobin B; mammaglobin-2
UniProt Protein Name
Mammaglobin-B
Protein Family
UniProt Gene Name
SCGB2A1
UniProt Synonym Gene Names
LIPHC; MGB2; UGB3
UniProt Entry Name
SG2A1_HUMAN

Uniprot Description

SCGB2A1: May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. Belongs to the secretoglobin family. Lipophilin subfamily.

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: extracellular space

Molecular Function: protein heterodimerization activity

Biological Process: androgen receptor signaling pathway

Research Articles on SCGB2A1

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Product Notes

The SCGB2A1 scgb2a1 (Catalog #AAA8121871) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Asn95. It is sometimes possible for the material contained within the vial of "Mammaglobin B/SCGB2A1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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