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Scavenger Receptor Class B Member 1 Recombinant Protein | SCARB1 recombinant protein
Recombinant Scavenger Receptor Class B Member 1 (SCARB1)
Source: Prokaryotic expression
PSLIKQQV LKNVRIDPSS LSFGMWKEIP VPFYLSVYFF EVVNPSEVLN GQKPVVRERG PYVYREFRQK VNITFNDNDT VSYIENRSLR FQPDRSQGSE SDYIVLPNIL VLGGAVMMED KPTSLKLLMT LGLVTMGQRA FMNRTVGEIL WGYEDPFVNF LSKYFPDMFP IKGKFGLFVG MNDSSSGVFT VFTGVQNFSK IHLVDKWNGL SEVNYWHSEQ CNMINGTAGQ MWAPFMTPES SLEFFSPEAC RSMKLTYQES RVFEGIPTYR FTAPDTLFAN GSVYPPNEGF CPCRESGIQN VSTCRFGAPL FLSQPHFYNA DPVLSEAVLG LNPDPKEHSL FLDIHPVTGI PMNCSVKMQL SLYIKSVKGV GQTGKIEPVV LPLLWFEQSG MMGGKTLNTF YTQLVLMPQV
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
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NCBI and Uniprot Product Information
Uniprot Description
SCARB1: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester. Belongs to the CD36 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, misc.
Cellular Component: cell surface; microvillus membrane; lysosomal membrane; integral to plasma membrane; cytoplasm; integral to membrane; plasma membrane; caveola
Molecular Function: apolipoprotein A-I binding; lipid transporter activity; protein homodimerization activity; lipopolysaccharide binding; phosphatidylserine binding; low-density lipoprotein binding; lipopolysaccharide receptor activity; apolipoprotein binding; high-density lipoprotein binding
Biological Process: receptor-mediated endocytosis; cholesterol transport; blood vessel endothelial cell migration; positive regulation of nitric-oxide synthase activity; cholesterol efflux; phagocytosis, recognition; androgen biosynthetic process; lipid transport; regulation of phagocytosis; recognition of apoptotic cell; lipopolysaccharide transport; cholesterol homeostasis; reverse cholesterol transport; endothelial cell proliferation; detection of lipopolysaccharide; lipopolysaccharide-mediated signaling pathway; adhesion to host; phospholipid transport; cholesterol catabolic process; cell adhesion; steroid biosynthetic process
Research Articles on SCARB1
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Product Notes
The SCARB1 scarb1 (Catalog #AAA2030568) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Scavenger Receptor Class B Member 1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the SCARB1 scarb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below.PSLIKQQV LKNVRIDPSS LSFGMWKEIP VPFYLSVYFF EVVNPSEVLN GQKPVVRERG PYVYREFRQK VNITFNDNDT VSYIENRSLR FQPDRSQGSE SDYIVLPNIL VLGGAVMMED KPTSLKLLMT LGLVTMGQRA FMNRTVGEIL WGYEDPFVNF LSKYFPDMFP IKGKFGLFVG MNDSSSGVFT VFTGVQNFSK IHLVDKWNGL SEVNYWHSEQ CNMINGTAGQ MWAPFMTPES SLEFFSPEAC RSMKLTYQES RVFEGIPTYR FTAPDTLFAN GSVYPPNEGF CPCRESGIQN VSTCRFGAPL FLSQPHFYNA DPVLSEAVLG LNPDPKEHSL FLDIHPVTGI PMNCSVKMQL SLYIKSVKGV GQTGKIEPVV LPLLWFEQSG MMGGKTLNTF YTQLVLMPQV
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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