Store-operated calcium entry-associated regulatory factor (TMEM66) Recombinant Protein | TMEM66 recombinant protein
Recombinant Pongo abelii Store-operated calcium entry-associated regulatory factor (TMEM66), partial
Gene Names
SARAF; TMEM66
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Store-operated calcium entry-associated regulatory factor (TMEM66); Recombinant Pongo abelii Store-operated calcium entry-associated regulatory factor (TMEM66); partial; TMEM66 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
195-339
Sequence
SDGQYS PPPYSEYPPF SHRYQRFTNS AGPPPPGFKS EFTGPQNTGH GATSGFGSAF TGQQGYENSG PGFWTGLGTG GILGYLFGSN RAATPFSDSW YYPSYPPSYP GTWNRAYSPL RGGSGSYSAC SNSDTKTRTA SGYGGTRRR
Sequence Length
145
Species
Pongo abelii (Sumatran orangutan)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,993 Da
NCBI Official Full Name
store-operated calcium entry-associated regulatory factor
NCBI Official Symbol
SARAF
NCBI Official Synonym Symbols
TMEM66
NCBI Protein Information
store-operated calcium entry-associated regulatory factor
UniProt Protein Name
Store-operated calcium entry-associated regulatory factor
UniProt Gene Name
SARAF
UniProt Synonym Gene Names
TMEM66; SARAF; SOCE-associated regulatory factor
Uniprot Description
Negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. In response to cytosolic Ca2+ elevation after endoplasmic reticulum Ca2+ refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca2+ levels, and thus preventing the overload of the cell with excessive Ca2+ ions ().
Similar Products
Product Notes
The TMEM66 saraf (Catalog #AAA1383981) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 195-339. The amino acid sequence is listed below: SDGQYS PPPYSEYPPF SHRYQRFTNS AGPPPPGFKS EFTGPQNTGH GATSGFGSAF TGQQGYENSG PGFWTGLGTG GILGYLFGSN RAATPFSDSW YYPSYPPSYP GTWNRAYSPL RGGSGSYSAC SNSDTKTRTA SGYGGTRRR. It is sometimes possible for the material contained within the vial of "Store-operated calcium entry-associated regulatory factor (TMEM66), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
