Bovine Serum Amyloid P Component ELISA Kit | SAP elisa kit

Bovine Serum Amyloid P Component ELISA Kit

Cat. Num. AAA43263

• Gene Names: APCS; SAP; PTX2
• Reactivity: Bovine
• Synonyms: Serum Amyloid P Component; Bovine Serum Amyloid P Component ELISA Kit; SAP elisa kit

• Reactivity: Bovine
• Specificity: No significant cross-reactivity or interference between Bovine SAP and analogues was observed.

• Samples: Mouse Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 25ng/ml-800ng/ml
• Sensitivity: 2.0ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SAP elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of SAM (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 4502133
• NCBI GeneID: 325
• NCBI Accession #: NP_001630.1
• NCBI GenBank Nucleotide #: NM_001639.3
• UniProt Accession #: P02743
• Molecular Weight: 25,387 Da
• NCBI Official Full Name: serum amyloid P-component
• NCBI Official Synonym Full Names: amyloid P component, serum
• NCBI Official Symbol: APCS
• NCBI Official Synonym Symbols: SAP; PTX2
• NCBI Protein Information: serum amyloid P-component; pentaxin-related; 9.5S alpha-1-glycoprotein
• UniProt Protein Name: Serum amyloid P-component
• Protein Family: S-layer protein
• UniProt Gene Name: APCS
• UniProt Synonym Gene Names: PTX2; SAP
• UniProt Entry Name: SAMP_HUMAN

NCBI Description

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]

Uniprot Description

APCS: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. Belongs to the pentaxin family.

Protein type: Secreted, signal peptide; Secreted; Chaperone

Chromosomal Location of Human Ortholog: 1q21-q23

Cellular Component: extracellular matrix; extracellular space; protein complex; extracellular region; nucleus

Molecular Function: complement component C1q binding; unfolded protein binding; virion binding; calcium ion binding; carbohydrate binding

Biological Process: protein folding; negative regulation of virion penetration into host cell; acute-phase response; negative regulation of acute inflammatory response; innate immune response; chaperone-mediated protein complex assembly; negative regulation of monocyte differentiation; negative regulation of viral reproduction