Two-component-system connector protein SafA (safA) Recombinant Protein | safA recombinant protein
Recombinant Escherichia coli Two-component-system connector protein SafA (safA), partial
NCBI and Uniprot Product Information
NCBI Description
A yneN(b1500) mutant has 3-fold lower acid resistance and is regulated by EvgA as the first gene in the yneN(b1500)-ydeO operon (Masuda, 2002). yneN is activated by EvgA to stimulate genes downstream of PhoP in a PhoP-dependent manner by binding to PhoQ in the membrane, although the start site was not verified, the cloned gene effects are not IPTG-dependent and no native protein expression was demonstrated (Eguki, 2007). [More information is available at EcoGene: EG14466]. B1500 is involved in signal transduction between the EvgS/EvgA and PhoQ/PhoP two-component signal transduction systems. [More information is available at EcoCyc: G6790].
Uniprot Description
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
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Product Notes
The safA safa (Catalog #AAA1017098) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-65. The amino acid sequence is listed below: MHATTVKNKI TQRDNYKEIM SAIVVVLLLT LTLIAIFSAI DQLSISEMGR IARDLTHFII NSLQG. It is sometimes possible for the material contained within the vial of "Two-component-system connector protein SafA (safA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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