Retinoic acid receptor RXR-beta (RXRB) Recombinant Protein | RXRB recombinant protein

Recombinant Human Retinoic acid receptor RXR-beta (RXRB)

Cat. Num. AAA965756

• Gene Names: RXRB; NR2B2; DAUDI6; RCoR-1; H-2RIIBP
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Retinoic acid receptor RXR-beta (RXRB); Recombinant Human Retinoic acid receptor RXR-beta (RXRB); RXRB recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-533, Full length protein
• Sequence: MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
• Sequence Length: 533

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for RXRB recombinant protein

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

NCBI and Uniprot Product Information

• NCBI GI #: 393715097
• NCBI GeneID: 6257
• NCBI Accession #: NP_001257330.1
• NCBI GenBank Nucleotide #: NM_001270401.1
• UniProt Accession #: P28702; P28703; Q59G65; Q5JP92; Q5STQ1
• Molecular Weight: 57,365 Da
• NCBI Official Full Name: retinoic acid receptor RXR-beta isoform 1
• NCBI Official Synonym Full Names: retinoid X receptor beta
• NCBI Official Symbol: RXRB
• NCBI Official Synonym Symbols: NR2B2; DAUDI6; RCoR-1; H-2RIIBP
• NCBI Protein Information: retinoic acid receptor RXR-beta
• UniProt Protein Name: Retinoic acid receptor RXR-beta
• Protein Family: Retinoic acid receptor
• UniProt Gene Name: RXRB
• UniProt Synonym Gene Names: NR2B2

NCBI Description

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Uniprot Description

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).