Sphingoid long-chain base transporter RSB1 (RSB1) Recombinant Protein | RSB1 recombinant protein
Recombinant Saccharomyces cerevisiae Sphingoid long-chain base transporter RSB1 (RSB1)
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalyzes the ATP-dependent translocation of sphingoid long-chain bases (LCBs) from the cytoplasmic site toward the extracytoplasmic side of the membrane (flip-flop). Involved in the establishment of the functional lipid asymmetry of the plasma membrane. Regulates intracellular levels of LCBs, shingolipid precursors that are growth inhibitory at increased levels
By similarity.
Subcellular location: Cell membrane
By similarity; Multi-pass membrane protein.
Induction: In response to loss of mitochondrial DNA in a transcription factor PDR3-dependent manner. Induced in response to altered glycerophospholipid asymmetry of the plasma membrane in a transcription factor PDR1-dependent manner
By similarity.
Sequence similarities: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family. [View classification]
Sequence caution: The sequence EEU08348.1 differs from that shown. Reason: Erroneous initiation.
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Product Notes
The Sphingoid long-chain base transporter RSB1 (RSB1) rsb1 (Catalog #AAA1043035) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-382. The amino acid sequence is listed below: MSNATNNTLG SLLPQLEAAA NSNSLYGGMV PNLRFNITMI VIWGILLTIH VVQLLMRQYW FSIAFICTGI LEVLGFIGRT WSHSNVADMD AFLLNMICLT IAPVFTMGGI YYQLAKLIEV YGHRFSLLPS PMAYSFIFIC SDIVSLVVQA VGGGLCGVAV TDGTSTTTGN HVFIAGLAIQ VASMAIFLML WFHFLFRIYI SVRWEHINSR PISLSLLKIS QTEVDYLYRE KFHFLRLEPK RWVFHYFNLA ITVAVLTIFT RCCYRLAELV VGWDGYLITH EWYFIILDAL MMAIATVTLT IFHPGFAFKG KSTSIPITPG HVDPETLPHT DDVEDILDTS DSKQFDIEKE EFQASMKYPI STFKQFMSKI ANLFSSKKKA KL. It is sometimes possible for the material contained within the vial of "Sphingoid long-chain base transporter RSB1 (RSB1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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