Human regulation of nuclear pre-mRNA domain containing 1A ELISA Kit | RPRD1A elisa kit
Human Regulation of nuclear pre-mRNA domain-containing protein 1A, RPRD1A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and may have a role in cell cycle regulation (Liu et al., 2002 [PubMed 12470661]).[supplied by OMIM, Mar 2008]
Uniprot Description
P15RS: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. Belongs to the UPF0400 (RTT103) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 18q12.2
Cellular Component: DNA-directed RNA polymerase II, holoenzyme
Research Articles on RPRD1A
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Product Notes
The Human RPRD1A rprd1a (Catalog #AAA9320098) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320098 ELISA Kit recognizes Human RPRD1A. It is sometimes possible for the material contained within the vial of "regulation of nuclear pre-mRNA domain containing 1A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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