60S ribosomal protein L17 Recombinant Protein | RPL17 recombinant protein

Recombinant human 60S ribosomal protein L17

Cat. Num. AAA717234

• Gene Names: RPL17; L17; PD-1; RPL23
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: 60S ribosomal protein L17; Recombinant human 60S ribosomal protein L17; Recombinant human 60S ribosomal protein L17 protein; RPL17 recombinant protein

• Host: E Coli
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Liquid containing glycerol
• Sequence: VRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE

• Preparation and Storage: Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.

SDS-PAGE

Related Product Information for RPL17 recombinant protein

Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, Colo 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line Mia Paca, and the pancreatic tumor cell lines of undefined differentiation status Panc 89 and SW 979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HGC 25 and Panc 1

References

[1] "A human gene related to the ribosomal protein L23 gene of Halobacterium marismortui."

NCBI and Uniprot Product Information

• NCBI GI #: 313569765
• NCBI GeneID: 6139
• NCBI Accession #: NP_000976.1
• NCBI GenBank Nucleotide #: NM_000985.4
• UniProt Accession #: P18621; Q3KQW2; Q6NZ54; Q7M4M5; B2R4H3
• Molecular Weight: 47 KD
• NCBI Official Full Name: Homo sapiens ribosomal protein L17 (RPL17), transcript variant 1, mRNA
• NCBI Official Synonym Full Names: ribosomal protein L17
• NCBI Official Symbol: RPL17
• NCBI Official Synonym Symbols: L17; PD-1; RPL23
• NCBI Protein Information: 60S ribosomal protein L17; 60S ribosomal protein L23; gene encoding putative NFkB activating protein
• UniProt Protein Name: 60S ribosomal protein L17
• Protein Family: 60S ribosomal protein
• UniProt Gene Name: RPL17
• UniProt Entry Name: RL17_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 2010]

Uniprot Description

Tissue specificity: Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, Colo 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line Mia Paca, and the pancreatic tumor cell lines of undefined differentiation status Panc 89 and SW 979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HGC 25 and Panc 1. Ref.2

Sequence similarities: Belongs to the ribosomal protein L22P family.