Uncharacterized protein yfjN (yfjN) Recombinant Protein | yfjN recombinant protein

Recombinant Escherichia coli Uncharacterized protein yfjN (yfjN)

Cat. Num. AAA1126199

• Gene Names: rnlA; ECK2626; JW2611; std; yfjN
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Uncharacterized protein yfjN (yfjN); Recombinant Escherichia coli Uncharacterized protein yfjN (yfjN); yfjN recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-357, full length protein
• Sequence: MTIRSYKNLNLVRANIETESRQFIENKNYSIQSIGPMPGSRAGLRVVFTRPGVNLATVDIFYNGDGSTTIQYLTGANRSLGQELADHLFETINPAEFEQVNMVLQGFVETSVLPVLELSADESHIEFREHSRNAHTVVWKIISTSYQDELTVSLHITTGKLQIQGRPLSCYRVFTFNLAALLDLQGLEKVLIRQEDGKANIVQQEVARTYLQTVMADAYPHLHVTAEKLLVSGLCVKLAAPDLPDYCMLLYPELRTIEGVLKSKMSGLGMPVQQPAGFGTYFDKPAAHYILKPQFAATLRPEQINIISTAYTFFNVERHSLFHMETVVDASRMISDMARLMGKATRAWGIIKDLYIV
• Sequence Length: 357

• Species: Escherichia coli (strain K12)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 16130548
• NCBI GeneID: 947107
• NCBI Accession #: NP_417119.1
• NCBI GenBank Nucleotide #: NC_000913.3
• UniProt Accession #: P52129; P76604; Q2MAE1
• Molecular Weight: 40,061 Da
• NCBI Official Full Name: CP4-57 prophage; RNase LS
• NCBI Official Symbol: rnlA
• NCBI Official Synonym Symbols: ECK2626; JW2611; std; yfjN
• NCBI Protein Information: CP4-57 prophage; RNase LS
• UniProt Protein Name: mRNA endoribonuclease toxin LS
• UniProt Gene Name: rnlA
• UniProt Synonym Gene Names: std; yfjN

NCBI Description

RnlA is responsible for the rapid degradation of T4 late genes in T4 dmd mutants. [More information is available at EcoGene: EG13200]. RNase LS is an endoribonuclease that cleaves bacteriophage T4 late mRNA in dmd mutant strains . [More information is available at EcoCyc: G7365].

Uniprot Description

Toxic component of a type II toxin-antitoxin (TA) system (PubMed:20980243, PubMed:24112600). A stable (half-life 27.6 minutes) endoribonuclease that in the absence of cognate antitoxin RnlB causes generalized RNA degradation. Degrades late enterobacteria phage T4 mRNAs, protecting the host against T4 reproduction. Activity is inhibited by cognate antitoxin RnlB and by enterobacteria phage T4 protein Dmd (PubMed:20980243, PubMed:22403819). Targets cyaA mRNA (PubMed:19019153).