E3 ubiquitin-protein ligase RNF135 (Rnf135) Recombinant Protein | Rnf135 recombinant protein
Recombinant Mouse E3 ubiquitin-protein ligase RNF135 (Rnf135)
Gene Names
Rnf135; 0610037N03Rik; 2410006N06Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
E3 ubiquitin-protein ligase RNF135 (Rnf135); Recombinant Mouse E3 ubiquitin-protein ligase RNF135 (Rnf135); Rnf135 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-417, full length protein
Sequence
MAAVCSGNAVPVWLSEDDLSCIICQGLLDQPTTLPCGHSFCLRCLHDLWVSKRGAVDGCPWACPICRKGPLTKPKLHKNPLLQDLVDKYLQAAREVEAGSEPEPAPAPRSAPQVTVQKSTTNVIQELTDMVRQLVDDVKSLQTQRPNLGSGQDNAQGTPPTDSSSEGEHSLDSPKLVTFSISQKKIQEILHNLEEIQEKLQGSVPGRAPPRERVQEMTSSLCLLPDQRRPAPRKASHLSLWAISPTFDLRTLSYNLEVSNNSRRVTVSRGDLHTYHWSPQRFSISQVFCSQALSSGQKYWEVDTRNCSHWAIGVASWGMKRDGMLGRTMDSWCIEWRGPGQFSAWAKMKKTDLQSDLPEVVGVWLDLESGELAFYAVADHERLLYECEVSSSSPLHPAFWLYGLSPGNYLEIKQLNT
Sequence Length
417
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Rnf135 recombinant protein
This protein contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,359 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase RNF135
NCBI Official Synonym Full Names
ring finger protein 135
NCBI Official Symbol
Rnf135
NCBI Official Synonym Symbols
0610037N03Rik; 2410006N06Rik
NCBI Protein Information
E3 ubiquitin-protein ligase RNF135
UniProt Protein Name
E3 ubiquitin-protein ligase RNF135
Protein Family
UniProt Gene Name
Rnf135
Uniprot Description
Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.
Research Articles on Rnf135
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Product Notes
The Rnf135 rnf135 (Catalog #AAA1363346) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-417, full length protein. The amino acid sequence is listed below: MAAVCSGNAV PVWLSEDDLS CIICQGLLDQ PTTLPCGHSF CLRCLHDLWV SKRGAVDGCP WACPICRKGP LTKPKLHKNP LLQDLVDKYL QAAREVEAGS EPEPAPAPRS APQVTVQKST TNVIQELTDM VRQLVDDVKS LQTQRPNLGS GQDNAQGTPP TDSSSEGEHS LDSPKLVTFS ISQKKIQEIL HNLEEIQEKL QGSVPGRAPP RERVQEMTSS LCLLPDQRRP APRKASHLSL WAISPTFDLR TLSYNLEVSN NSRRVTVSRG DLHTYHWSPQ RFSISQVFCS QALSSGQKYW EVDTRNCSHW AIGVASWGMK RDGMLGRTMD SWCIEWRGPG QFSAWAKMKK TDLQSDLPEV VGVWLDLESG ELAFYAVADH ERLLYECEVS SSSPLHPAFW LYGLSPGNYL EIKQLNT. It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase RNF135 (Rnf135), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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