Ribonuclease pancreatic (RNASE1) Recombinant Protein | RNASE1 recombinant protein

Recombinant Human Ribonuclease pancreatic (RNASE1)

Cat. Num. AAA953564

• Gene Names: RNASE1; RAC1; RIB1; RNS1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Ribonuclease pancreatic (RNASE1); Recombinant Human Ribonuclease pancreatic (RNASE1); RNASE1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 29-156, Full length protein
• Sequence: KESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST
• Sequence Length: 128

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for RNASE1 recombinant protein

This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3 -side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2 ,3 -cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

NCBI and Uniprot Product Information

• NCBI GI #: 4506547
• NCBI GeneID: 6035
• NCBI Accession #: NP_002924.1
• NCBI GenBank Nucleotide #: NM_002933.4
• UniProt Accession #: P07998; Q16830; Q16869; Q1KHR2; Q6ICS5; Q9UCB4; Q9UCB5; B2R589; D3DS06
• Molecular Weight: 17,644 Da
• NCBI Official Full Name: ribonuclease pancreatic
• NCBI Official Synonym Full Names: ribonuclease A family member 1, pancreatic
• NCBI Official Symbol: RNASE1
• NCBI Official Synonym Symbols: RAC1; RIB1; RNS1
• NCBI Protein Information: ribonuclease pancreatic
• UniProt Protein Name: Ribonuclease pancreatic
• Protein Family: Ribonuclease pancreatic
• UniProt Gene Name: RNASE1
• UniProt Synonym Gene Names: RIB1; RNS1; RNase 1; RNase A

NCBI Description

This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.