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RIOK1 / Serine/Threonine-Protein Kinase RIO1 Recombinant Protein | RIOK1 recombinant protein

Human RIOK1 / Serine/Threonine-Protein Kinase RIO1 Recombinant Protein

Gene Names
RIOK1; RIO1; AD034; RRP10; bA288G3.1
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
RIOK1 / Serine/Threonine-Protein Kinase RIO1; Human RIOK1 / Serine/Threonine-Protein Kinase RIO1 Recombinant Protein; Serine/threonine-protein kinase RIO1; RIO kinase 1; RIOK1 recombinant protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
568
Applicable Applications for RIOK1 recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Associates with the precursor of the 40S ribosome subunit. Interacts with PRMT5 and WDR77.
Entry Function
Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor (PubMed:22072790). The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its dynamic association with the 40S subunit.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
serine/threonine-protein kinase RIO1 isoform 1
NCBI Official Synonym Full Names
RIO kinase 1
NCBI Official Symbol
RIOK1
NCBI Official Synonym Symbols
RIO1; AD034; RRP10; bA288G3.1
NCBI Protein Information
serine/threonine-protein kinase RIO1
UniProt Protein Name
Serine/threonine-protein kinase RIO1
UniProt Gene Name
RIOK1

NCBI Description

The protein encoded by this gene competes with pICln for inclusion in the protein arginine methyltransferase 5 complex. This complex targets substrates for dimethylation. The encoded protein is essential for the last steps in the maturation of 40S subunits. [provided by RefSeq, Jan 2017]

Research Articles on RIOK1

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Product Notes

The RIOK1 riok1 (Catalog #AAA2903264) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RIOK1 / Serine/Threonine-Protein Kinase RIO1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the RIOK1 riok1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIOK1 / Serine/Threonine-Protein Kinase RIO1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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