Mouse regulating synaptic membrane exocytosis 1 ELISA Kit | RIMS1 elisa kit
Mouse Regulating synaptic membrane exocytosis protein 1, RIMS1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
RIMS1: a Rab effector protein involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short- term synaptic plasticity. Binds UNC13, SNAP25, SYT1, CACNA1B, and activated RAB3A, RAB3B and RAB3D. Interaction with SYT1 is enhanced by calcium ions. Interaction with SNAP25 is weaker in the presence of calcium ions. Defects are a cause of autosomal dominant cone-rod dystrophy (CORD7). Eight splice-variant isoforms have been described.
Protein type: Adaptor/scaffold; Vesicle
Cellular Component: presynaptic membrane; membrane; cell; postsynaptic density; plasma membrane; synapse; cell junction
Molecular Function: protein binding; metal ion binding; SH3 domain binding; protein kinase binding; Rab GTPase binding
Biological Process: regulation of long-term neuronal synaptic plasticity; intracellular protein transport; regulation of membrane potential; exocytosis; neurotransmitter transport; transport; calcium ion-dependent exocytosis of neurotransmitter; protein complex assembly
Research Articles on RIMS1
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Product Notes
The Mouse RIMS1 rims1 (Catalog #AAA9342569) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342569 ELISA Kit recognizes Mouse RIMS1. It is sometimes possible for the material contained within the vial of "regulating synaptic membrane exocytosis 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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