Rat resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) ELISA Kit | RIC8B elisa kit
Rat Synembryn-B, RIC8B ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
binds heterotrimeric G proteins; may act as a nonreceptor guanine nucleotide exchange factor [RGD, Feb 2006]
Uniprot Description
RIC8B: a guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. Interacts with GDP-bound G alpha proteins GNAI1, GNAL, GNAS and GNAQ. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma. Belongs to the synembryn family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, misc.
Cellular Component: centrosome; cytoplasm; plasma membrane; cell cortex; cytosol
Molecular Function: guanyl-nucleotide exchange factor activity; G-protein alpha-subunit binding; GTPase activator activity
Biological Process: G-protein coupled receptor protein signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity
Research Articles on RIC8B
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Product Notes
The Rat RIC8B ric8b (Catalog #AAA9341886) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9341886 ELISA Kit recognizes Rat RIC8B. It is sometimes possible for the material contained within the vial of "resistance to inhibitors of cholinesterase 8 homolog B (C. elegans), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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