Rhomboid-related protein 1 (RHBDL1) Recombinant Protein | RHBDL1 recombinant protein
Recombinant Human Rhomboid-related protein 1 (RHBDL1)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Uniprot Description
RHBDL1: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Belongs to the peptidase S54 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Protease; Membrane protein, multi-pass; EC 3.4.21.105
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: integral to plasma membrane; membrane; mitochondrial inner membrane
Molecular Function: serine-type endopeptidase activity
Biological Process: protein processing; signal transduction
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Product Notes
The RHBDL1 rhbdl1 (Catalog #AAA7028547) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-438aa; Full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the RHBDL1 rhbdl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGRVEDGGTT EELEDWDPGT SALPAPGIKQ GPREQTGTGP LSQKCWEPEP DAPSQPGPAL WSRGRARTQA LAGGSSLQQL DPENTGFIGA DTFTGLVHSH ELPLDPAKLD MLVALAQSNE QGQVCYQELV DLISSKRSSS FKRAIANGQR ALPRDGPLDE PGLGVYKRFV RYVAYEILPC EVDRRWYFYR HRSCPPPVFM ASVTLAQIIV FLCYGARLNK WVLQTYHPEY MKSPLVYHPG HRARAWRFLT YMFMHVGLEQ LGFNALLQLM IGVPLEMVHG LLRISLLYLA GVLAGSLTVS ITDMRAPVVG GSGGVYALCS AHLANVVMNW AGMRCPYKLL RMVLALVCMS SEVGRAVWLR FSPPLPASGP QPSFMAHLAG AVVGVSMGLT ILRSYEERLR DQCGWWVVLL AYGTFLLFAV FWNVFAYDLL GAHIPPPP. It is sometimes possible for the material contained within the vial of "Rhomboid-related protein 1 (RHBDL1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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