Human rhomboid 5 homolog 2 (Drosophila) ELISA Kit | RHBDF2 elisa kit
Human Inactive rhomboid protein 2, RHBDF2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
RHBDL6: Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration. Defects in RHBDF2 are the cause of tylosis with esophageal cancer (TOC). An autosomal dominant syndrome characterized by diffuse palmoplantar keratoderma, oral leukokeratosis, and a high lifetime risk of esophageal cancer. Belongs to the peptidase S54 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: endoplasmic reticulum membrane; plasma membrane; integral to membrane
Molecular Function: growth factor binding; serine-type endopeptidase activity
Biological Process: protein transport; negative regulation of protein secretion; proteolysis
Disease: Tylosis With Esophageal Cancer
Research Articles on RHBDF2
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Product Notes
The Human RHBDF2 rhbdf2 (Catalog #AAA9319400) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319400 ELISA Kit recognizes Human RHBDF2. It is sometimes possible for the material contained within the vial of "rhomboid 5 homolog 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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