Human Regulator of G-protein signaling 9 ELISA Kit | RGS9 elisa kit
Human Regulator of G-protein signaling 9 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Uniprot Description
RGS9: belongs to the 'regulator of G protein signaling' family. Inhibits signal transduction by increasing the GTPAse activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction. Four alternatively spliced isoforms have been described.
Protein type: GAPs, RGS; GAPs
Chromosomal Location of Human Ortholog: 17q24
Cellular Component: cytoplasm; heterotrimeric G-protein complex; nucleus; photoreceptor inner segment; photoreceptor outer segment; plasma membrane
Molecular Function: GTPase activator activity; protein complex binding; signal transducer activity
Biological Process: dopamine receptor signaling pathway; negative regulation of signal transduction; nervous system development; phototransduction, visible light; positive regulation of GTPase activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of rhodopsin mediated signaling; response to estrogen stimulus; rhodopsin mediated signaling; visual perception
Disease: Prolonged Electroretinal Response Suppression
Research Articles on RGS9
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Product Notes
The Human RGS9 rgs9 (Catalog #AAA2885250) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885250 ELISA Kit recognizes Human RGS9. It is sometimes possible for the material contained within the vial of "Regulator of G-protein signaling 9, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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