RGS16 recombinant protein

RGS16, 1-202aa, Human, His tag, E Coli

Cat. Num. AAA203424

• Gene Names: RGS16; RGS-R; A28-RGS14; A28-RGS14P
• Applications: SDS-Page
• Purity: > 90% by SDS-PAGE
• Synonyms: RGS16; 1-202aa; Human; His tag; E Coli; Regulator of G-protein signaling 16; A28-RGS14; A28-RGS14P; RGS-R; Regulator of G-protein signaling 16 A28 RGS14; A28 RGS14P; HGNC:9997; Regulator of G protein signaling 16; Retinally abundant regulator of G protein signaling; RGS 16 RGS R; Rgs14; RGSR.; RGS16 recombinant protein

• Host: E Coli
• Purity/Purification: > 90% by SDS-PAGE
• Form/Format: Liquid. In phosphate buffered saline (pH 7.4) containing 20% glycerol, 0.1M NaCl
• Concentration: 0.5 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT
• Sequence Length: 202

• Applicable Applications for RGS16 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for RGS16 recombinant protein

RGS16, also known as regulator of G-protein signaling 16, belongs to 'regulator of G protein signaling' family and negatively regulates G protein coupled receptor signalling. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP bound form. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. Recombinant RGS16 protein was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for RGS16 recombinant protein

Signal Transduction

References

Chen C., et al. (1997) J Biol Chem. 272 (13):8679-85; Derrien A., et al. (2001) J Biol Chem. 276 (51):48532-8;

NCBI and Uniprot Product Information

• NCBI GI #: 13623285
• NCBI GeneID: 6004
• Molecular Weight: 24.9 kDa (222aa), confirmed by MALDI-TOF.
• NCBI Official Full Name: Regulator of G-protein signaling 16
• NCBI Official Synonym Full Names: regulator of G protein signaling 16
• NCBI Official Symbol: RGS16
• NCBI Official Synonym Symbols: RGS-R; A28-RGS14; A28-RGS14P
• NCBI Protein Information: regulator of G-protein signaling 16
• UniProt Protein Name: Regulator of G-protein signaling 16
• Protein Family: Regulator of G-protein signaling
• UniProt Gene Name: RGS16
• UniProt Synonym Gene Names: RGSR; RGS16; RGS-r; hRGS-r

NCBI Description

The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]

Uniprot Description

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541). Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals ().