Replication-associated protein (rep) Recombinant Protein | rep recombinant protein
Recombinant Goose circovirus Replication-associated protein (rep)
NCBI and Uniprot Product Information
Uniprot Description
Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep and/or Rep' binds a specific hairpin at the genome origin of replication. Introduces an endonucleolytic nick within the conserved sequence 5'-AGTATTAC-3' in the intergenic region of the genome, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities. ATPase activity is probably carried by the isoform Rep ().
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Product Notes
The rep rep (Catalog #AAA1480289) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-293aa; full length protein. The amino acid sequence is listed below: MAKNGNYSYK RWVFTINNPT FEDYCAVVEF CNLDNCKFAI VGEEKGEKEG TPHLQGFLSL RKNAKAAALE ENLGGRAWLS RARGSDEDNE EYCSKESTYL RVGEPNRKGR SSDLPDAASD VLAGLPITDV ARKYPTTYVM FGRGLERLRQ LIVETARDWK TEVIVLIGRP GSGKSRYAFE FPAREKYYKS RGKWWDGYNG QDVVVMDDFY GWLPYDDLLR ICDRYPLRVE YKGGMTQFVA KTLIITSNRE PRDWYKCEFD VSALYRRINQ YLILTPDGYA PAPEFMLPFK INY. It is sometimes possible for the material contained within the vial of "Replication-associated protein (rep), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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