PyBOP Reagent
PyBOP
Purity
0.99
Synonyms
PyBOP; Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate; (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate; PyBOP reagent
Purity/Purification
0.99
Molecular Formula
C18H28N6OPPF6
CAS Number
[128625-52-5
Preparation and Storage
Store at 2-10 degree C
Related Product Information for PyBOP reagent
Analogue of the BOP coupling reagent which does not form carcinogenic HMPA as by-product. Coupling reactions are rapid, being nearly complete within a few minutes. May be used in place of BOP in peptide synthesis without loss of coupling efficiency. Especially useful for cyclization steps for the activation of hindered amino acid.
Product Categories/Family for PyBOP reagent
References
J. Putura, P.M. Turunen, M.H. Jäntti, M.E. Ekholm, and J.P. Kukkonen, Neurosci. Lett., 494, 57 (2011). (Pharmacol.)
D. Le-Nguyen,B. Castro, PyBOP: A new peptide coupling reagent devoid of toxic by-product
S. Asahi, S.-I. Egashira, M. Matsuda, H. Iwaasa, A. Kanatani, M. Ohkubo, M. Ihara, and H. Morishima, Bioorg. Med. Chem. Lett., 13, 111 (2003). (Original; Structure-Activity Relationship & Pharmacol.)
D. Le-Nguyen,B. Castro, PyBOP: A new peptide coupling reagent devoid of toxic by-product
S. Asahi, S.-I. Egashira, M. Matsuda, H. Iwaasa, A. Kanatani, M. Ohkubo, M. Ihara, and H. Morishima, Bioorg. Med. Chem. Lett., 13, 111 (2003). (Original; Structure-Activity Relationship & Pharmacol.)
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Product Notes
The PyBOP (Catalog #AAA407520) is a Reagent and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PyBOP, Reagent" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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