RCC1 domain-containing protein 1 (RCCD1) Recombinant Protein | RCCD1 recombinant protein
Recombinant Macaca fascicularis RCC1 domain-containing protein 1 (RCCD1)
NCBI and Uniprot Product Information
Uniprot Description
Acts as a coregulator of KDM8 to promote histone demethylase activity on di- and trimethylated 'Lys-36' (H3K36me2/me3) of histone H3. Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability and thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.
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Product Notes
The RCCD1 rccd1 (Catalog #AAA1410469) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-376, Full length protein. The amino acid sequence is listed below: MAEERPGAWF GFGFCGFGQE LGSGRGHQVH SPSPLRAGVD VCRVSASWSY TAFVTRGGRV ELSGSASGAA GGCRDAWASE GLLLVLRAGP GPEALLQAWA PDSALRGEPL WAHSVVPEAV EEDDPGGEAQ IGRLPLLPCA RAYVSPRPPF YRPLAPELRA RQLELGAEHA LLLDAAGQVF SWGGGRHGQL GHGTLEAELE PRLLEALQGL TMAEVAAGGW HSVCVSETGD IYIWGWNESG QLALPTRNLA EDGETVAREA TGLNEDGSQV KRTGRVEDGA PAPFIAVQPF PALLDLPLGS DAVKVSCGSR HTAVVTRTGE LYTWGWGKYG QLGHEDTTSL DWPRRVEYFV DKQLQVKAVT CGPWNTYVYA VEKGKS. It is sometimes possible for the material contained within the vial of "RCC1 domain-containing protein 1 (RCCD1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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