Mouse RNA binding motif protein 25 ELISA Kit | RBM25 elisa kit
Mouse RNA-binding protein 25, RBM25 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
RBM25: RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA splicing; RNA-binding; Spliceosome
Cellular Component: cytoplasm; nucleus
Molecular Function: nucleic acid binding; RNA binding; nucleotide binding
Biological Process: apoptosis; RNA splicing; mRNA processing
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Product Notes
The Mouse RBM25 rbm25 (Catalog #AAA9322695) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322695 ELISA Kit recognizes Mouse RBM25. It is sometimes possible for the material contained within the vial of "RNA binding motif protein 25, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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